{"source":"PeptideWiki","url":"https://www.peptide-wiki.net","description":"Comprehensive peptide research database — 94+ compounds with clinical data, dosage protocols, and pricing.","license":"Research and educational use. See https://www.peptide-wiki.net/about for terms.","count":50,"data":[{"name":"5-Amino-1MQ","slug":"5-amino-1mq","url":"https://www.peptide-wiki.net/peptides/5-amino-1mq","aliases":["5-Amino-1-methylquinolinium","5A1MQ"],"category":{"id":"e468247c-9d2d-4c47-8c72-623f273726e6","name":"Weight Management","slug":"weight-management"},"research_status":"research_only","research_status_label":"Research Use Only","administration_routes":["oral"],"half_life":null,"summary":"A small molecule inhibitor of NNMT enzyme that boosts metabolism and promotes fat cell apoptosis. Shows promise as a novel anti-obesity agent in preclinical research.","mechanism":"NNMT is an enzyme that suppresses the metabolic rate. 5-Amino-1MQ blocks NNMT, increases the NAD+/NADH ratio, activates SIRT1, and upregulates metabolic pathways leading to fat reduction.","benefits":["Inhibits NNMT to boost resting metabolic rate","Promotes fat cell shrinkage and apoptosis","Increases NAD+ levels","Potential for muscle sparing during weight loss"],"side_effects":["Limited human data available","Potential GI discomfort"],"dosage_info":{"unit":"mg","notes":"Research compound with limited human clinical data.","max_dose":100,"min_dose":50,"frequency":"Once or twice daily oral","weight_based":false},"cycle_length":"4-8 weeks","stack_with":[{"slug":"semaglutide","url":"https://www.peptide-wiki.net/peptides/semaglutide"},{"slug":"aod-9604","url":"https://www.peptide-wiki.net/peptides/aod-9604"}],"molecular":{"formula":"C10H12N2","weight":null,"amino_acid_count":null,"cas_number":null,"pubchem_cid":null,"pubchem_url":null},"wada_banned":false,"wikipedia_url":null,"pricing":{"lowest_price_usd":58,"vendor_count":3,"in_stock_vendor_count":3,"vendors":[{"name":"Modern Aminos","price_usd":58,"quantity_mg":3000,"form":"oral","in_stock":true,"buy_url":"https://modernaminos.com/?ref=bre","discount_code":"BRE"},{"name":"Modified Aminos","price_usd":89.99,"quantity_mg":3000,"form":"oral","in_stock":true,"buy_url":"https://modifiedaminos.shop/?ref=bre","discount_code":"BRE"},{"name":"Vandl Labs","price_usd":124.99,"quantity_mg":3000,"form":"oral","in_stock":true,"buy_url":"https://vandl-labs.com/?ref=BRE","discount_code":"BRE"}]}},{"name":"ACE-031","slug":"ace-031","url":"https://www.peptide-wiki.net/peptides/ace-031","aliases":["ACVR2B-Fc","Activin receptor type IIB decoy","Myostatin inhibitor fusion protein"],"category":{"id":"d2d9a29b-8c74-405c-91d8-d5223b400dd5","name":"Body Composition","slug":"body-composition"},"research_status":"research_only","research_status_label":"Research Use Only","administration_routes":["subcutaneous injection"],"half_life":null,"summary":"A fusion protein combining the ligand-binding domain of the activin type IIB receptor (ACVR2B) with the Fc region of human IgG1. Acts as a decoy receptor for multiple TGF-beta superfamily members including myostatin, activin A, GDF-11, and BMP9, simultaneously blocking all of them to produce dramatic increases in muscle mass.","mechanism":"ACE-031 presents a decoy ACVR2B domain that captures myostatin, activin A, GDF-11, GDF-8, and other TGF-beta family ligands before they can bind to their native receptors. This removes multiple simultaneous brakes on muscle growth. In a Phase 2 trial for Duchenne muscular dystrophy, a single dose increased total lean mass by an average of 2.5 kg within 4 weeks.","benefits":["Simultaneous inhibition of multiple muscle-growth inhibitors (myostatin, activin A, GDF-11)","Dramatic lean mass increases — 2.5 kg in 4 weeks in Phase 2 DMD trial","Superior to single myostatin inhibitors or follistatin alone","Potential for muscle wasting diseases (DMD, ALS, cachexia)","Anti-aging muscle preservation"],"side_effects":["Epistaxis (nosebleeds) — most common side effect in trials","Gum bleeding","Telangiectasias (dilated capillaries)","Development halted in Phase 2 due to vascular side effects","Serious research compound — vascular safety concerns"],"dosage_info":{"unit":"mg/kg","notes":"Phase 2 DMD: 1-3mg/kg single SC dose produced 2.5 kg lean mass increase in 4 weeks. Development halted due to vascular side effects (epistaxis, telangiectasias). Research use only with caution.","max_dose":3,"min_dose":1,"frequency":"Single dose or monthly research protocol","weight_based":true},"cycle_length":"Monthly cycles or as directed","stack_with":[{"slug":"follistatin-344","url":"https://www.peptide-wiki.net/peptides/follistatin-344"},{"slug":"igf-1-lr3","url":"https://www.peptide-wiki.net/peptides/igf-1-lr3"}],"molecular":{"formula":null,"weight":"~55,000 Da (fusion protein)","amino_acid_count":null,"cas_number":"948557-43-5","pubchem_cid":null,"pubchem_url":null},"wada_banned":true,"wikipedia_url":null,"pricing":{"lowest_price_usd":99.99,"vendor_count":1,"in_stock_vendor_count":1,"vendors":[{"name":"PeptideTech","price_usd":99.99,"quantity_mg":1,"form":"injectable","in_stock":true,"buy_url":"https://peptidetech.co/?ref=bre&utm_source=affiliate","discount_code":"BRE"}]}},{"name":"Adipotide","slug":"adipotide","url":"https://www.peptide-wiki.net/peptides/adipotide","aliases":["FTPP","Proapoptotic Peptide"],"category":{"id":"331638a6-1066-49e5-9186-33cfc08ae05d","name":"Experimental","slug":"experimental"},"research_status":"research_only","research_status_label":"Research Use Only","administration_routes":["subcutaneous injection"],"half_life":null,"summary":"A highly experimental proapoptotic peptide that selectively destroys the blood supply to white adipose tissue. Dramatic fat loss in animal models but significant renal toxicity concerns.","mechanism":"Adipotide targets vasculature surrounding white adipose tissue and causes programmed death of adipocytes by cutting off their blood supply.","benefits":["Dramatic fat reduction in animal models","Highly targeted to adipose tissue"],"side_effects":["Significant renal toxicity - MOST SERIOUS CONCERN","Dehydration","Reduced kidney function","NOT recommended for human use","Limited human data"],"dosage_info":{"unit":"mcg/kg","notes":"CAUTION: Significant renal toxicity. Research compound only.","max_dose":null,"min_dose":null,"frequency":"Research only - no established human protocol","weight_based":true},"cycle_length":"Research only","stack_with":[],"molecular":{"formula":null,"weight":null,"amino_acid_count":null,"cas_number":null,"pubchem_cid":null,"pubchem_url":null},"wada_banned":false,"wikipedia_url":null,"pricing":{"lowest_price_usd":69.99,"vendor_count":1,"in_stock_vendor_count":1,"vendors":[{"name":"PeptideTech","price_usd":69.99,"quantity_mg":5,"form":"injectable","in_stock":true,"buy_url":"https://peptidetech.co/?ref=bre&utm_source=affiliate","discount_code":"BRE"}]}},{"name":"AHK-Cu","slug":"ahk-cu","url":"https://www.peptide-wiki.net/peptides/ahk-cu","aliases":["AHK copper peptide","Ala-His-Lys copper","AHK tripeptide"],"category":{"id":"ee678b1c-f2a5-4ab6-94fa-4d5f0dc4ee2b","name":"Anti-Aging & Longevity","slug":"anti-aging"},"research_status":"research_only","research_status_label":"Research Use Only","administration_routes":["topical","subcutaneous injection"],"half_life":null,"summary":"A tripeptide (Ala-His-Lys) copper complex that acts as a hair follicle stimulant, distinct from GHK-Cu. AHK-Cu specifically activates hair follicle stem cells and has been shown in in vitro studies to increase hair follicle size and activity by 153%, making it more hair-growth focused than GHK-Cu while sharing similar anti-aging and wound healing properties.","mechanism":"AHK-Cu binds and activates stem cell factor (SCF) receptor (c-Kit) on hair follicle stem cells, promoting follicle cycling from telogen (resting) to anagen (growth) phase. It also upregulates Wnt signaling in the hair follicle niche, a critical pathway for hair growth. The copper coordination enhances tissue penetration and collagen synthesis similar to GHK-Cu.","benefits":["Increases hair follicle size by up to 153% in in vitro studies","Activates hair follicle stem cells via c-Kit/SCF pathway","Upregulates Wnt signaling for hair growth","Anti-aging and skin rejuvenation effects similar to GHK-Cu","Collagen synthesis promotion","Wound healing acceleration","Synergistic with GHK-Cu for comprehensive skin/hair protocols"],"side_effects":["Generally very well tolerated","Mild scalp irritation initially","Limited long-term human clinical data"],"dosage_info":{"unit":"% concentration","notes":"Topical: 1-3% in carrier solution, applied daily to scalp or affected area. Also available as injectable for systemic use.","max_dose":null,"min_dose":null,"frequency":"Daily topical application to scalp or skin","weight_based":false},"cycle_length":"Ongoing","stack_with":[{"slug":"ghk-cu","url":"https://www.peptide-wiki.net/peptides/ghk-cu"},{"slug":"snap-8","url":"https://www.peptide-wiki.net/peptides/snap-8"}],"molecular":{"formula":null,"weight":"420 Da (estimated)","amino_acid_count":3,"cas_number":null,"pubchem_cid":null,"pubchem_url":null},"wada_banned":false,"wikipedia_url":null,"pricing":{"lowest_price_usd":39.99,"vendor_count":1,"in_stock_vendor_count":1,"vendors":[{"name":"PeptideTech","price_usd":39.99,"quantity_mg":50,"form":"topical","in_stock":true,"buy_url":"https://peptidetech.co/?ref=bre&utm_source=affiliate","discount_code":"BRE"}]}},{"name":"AICAR","slug":"aicar","url":"https://www.peptide-wiki.net/peptides/aicar","aliases":["Acadesine","AICA-riboside","5-Aminoimidazole-4-carboxamide ribonucleotide"],"category":{"id":"e468247c-9d2d-4c47-8c72-623f273726e6","name":"Weight Management","slug":"weight-management"},"research_status":"research_only","research_status_label":"Research Use Only","administration_routes":["subcutaneous injection","intravenous injection"],"half_life":"2-3 hours","summary":"A naturally occurring nucleoside and potent AMPK (AMP-activated protein kinase) activator. Mimics the cellular effects of exercise by activating energy-sensing pathways. Studied for metabolic disease, exercise performance, fat oxidation, and cancer treatment.","mechanism":"AICAR is converted intracellularly to ZMP, which mimics AMP and activates AMPK — the master metabolic switch. This leads to increased fatty acid oxidation, glucose uptake, improved insulin sensitivity, and mitochondrial biogenesis. In animal studies, AICAR alone increased endurance capacity by 44% and altered gene expression in skeletal muscle to an endurance phenotype.","benefits":["Activates AMPK — the master metabolic regulator","Increases fat oxidation and fatty acid metabolism","Improves insulin sensitivity and glucose uptake","Exercise-mimetic properties (increases endurance gene expression)","Studied for metabolic syndrome, type 2 diabetes, NAFLD","Cancer research (pro-apoptotic in some cancer cell lines)","Cardiovascular protection during ischemia"],"side_effects":["Hypoglycemia risk (increases glucose uptake)","Headache","Nausea","Potential cardiac arrhythmia at high doses","Not cleared for human use beyond specific cardiac surgical settings"],"dosage_info":{"unit":"mg","notes":"CAUTION: Research compound with significant metabolic effects. Hypoglycemia risk. Use only in controlled research settings.","max_dose":1000,"min_dose":500,"frequency":"Once daily subcutaneous injection or IV","weight_based":false},"cycle_length":"2-4 weeks","stack_with":[{"slug":"mots-c","url":"https://www.peptide-wiki.net/peptides/mots-c"},{"slug":"semaglutide","url":"https://www.peptide-wiki.net/peptides/semaglutide"}],"molecular":{"formula":"C9H14N4O5","weight":"258.23 Da","amino_acid_count":0,"cas_number":"2627-69-2","pubchem_cid":"17513","pubchem_url":"https://pubchem.ncbi.nlm.nih.gov/compound/17513"},"wada_banned":false,"wikipedia_url":"https://en.wikipedia.org/wiki/Acadesine","pricing":{"lowest_price_usd":null,"vendor_count":0,"in_stock_vendor_count":0,"vendors":[]}},{"name":"AOD-9604","slug":"aod-9604","url":"https://www.peptide-wiki.net/peptides/aod-9604","aliases":["AOD9604","HGH Fragment 176-191","Frag 176-191"],"category":{"id":"e468247c-9d2d-4c47-8c72-623f273726e6","name":"Weight Management","slug":"weight-management"},"research_status":"research_only","research_status_label":"Research Use Only","administration_routes":["subcutaneous injection","oral"],"half_life":"Short (minutes)","summary":"A synthetic fragment of the C-terminus of HGH (amino acids 176-191) that retains the fat-burning properties of growth hormone without affecting blood sugar or IGF-1 levels.","mechanism":"AOD-9604 stimulates lipolysis and inhibits lipogenesis by mimicking the way endogenous HGH regulates fat metabolism. Unlike full HGH, it does not affect insulin-like growth factor levels.","benefits":["Targeted fat reduction without systemic HGH effects","Stimulates lipolysis","Inhibits fat storage","No effect on blood sugar or insulin","No effect on IGF-1","Prevents diet-induced obesity in animal models"],"side_effects":["Mild headaches","Indigestion","Injection site flushing or swelling","Mild nausea"],"dosage_info":{"unit":"mcg","notes":"Most effective when taken fasted. 20-day research cycles.","max_dose":500,"min_dose":250,"frequency":"Once daily, on an empty stomach","weight_based":false},"cycle_length":"20 days","stack_with":[{"slug":"cjc-1295","url":"https://www.peptide-wiki.net/peptides/cjc-1295"},{"slug":"ipamorelin","url":"https://www.peptide-wiki.net/peptides/ipamorelin"}],"molecular":{"formula":"C78H123N23O23S2","weight":"1,815.1 Da","amino_acid_count":16,"cas_number":"221231-10-3","pubchem_cid":"71300630","pubchem_url":"https://pubchem.ncbi.nlm.nih.gov/compound/71300630"},"wada_banned":false,"wikipedia_url":"https://en.wikipedia.org/wiki/AOD9604","pricing":{"lowest_price_usd":44.99,"vendor_count":4,"in_stock_vendor_count":4,"vendors":[{"name":"Modified Aminos","price_usd":44.99,"quantity_mg":5,"form":"nasal_spray","in_stock":true,"buy_url":"https://modifiedaminos.shop/?ref=bre","discount_code":"BRE"},{"name":"PeptideTech","price_usd":49.99,"quantity_mg":5,"form":"injectable","in_stock":true,"buy_url":"https://peptidetech.co/?ref=bre&utm_source=affiliate","discount_code":"BRE"},{"name":"Modern Aminos","price_usd":54,"quantity_mg":5,"form":"injectable","in_stock":true,"buy_url":"https://modernaminos.com/?ref=bre","discount_code":"BRE"},{"name":"FelixChem","price_usd":59.99,"quantity_mg":5,"form":"injectable","in_stock":true,"buy_url":"https://felixchem.is/refer/642/","discount_code":"Bre10"}]}},{"name":"ARA-290","slug":"ara-290","url":"https://www.peptide-wiki.net/peptides/ara-290","aliases":["Cibinetide","ARA290"],"category":{"id":"c74901aa-1014-4a30-ad71-de1c16e394b1","name":"Healing & Recovery","slug":"healing-recovery"},"research_status":"clinical_trials","research_status_label":"In Human Clinical Trials","administration_routes":["subcutaneous injection"],"half_life":null,"summary":"A synthetic 11-amino acid peptide that mimics the tissue-protective actions of erythropoietin without its erythropoietic effects. Highly effective for neuropathic pain and nerve repair.","mechanism":"ARA-290 acts on the innate repair receptor (IRR), reducing nerve-level inflammation, promoting nerve fiber regeneration, and rapidly penetrating the CNS.","benefits":["Reduces neuropathic pain significantly","Promotes peripheral nerve regeneration","Reduces nerve inflammation","Penetrates the blood-brain barrier","Investigated for TBI and sarcoidosis"],"side_effects":["Headache","Injection site reactions","Potential blood pressure changes"],"dosage_info":{"unit":"mg","notes":"4-week cycles studied in clinical trials for neuropathic pain.","max_dose":8,"min_dose":4,"frequency":"Once daily subcutaneous injection","weight_based":false},"cycle_length":"4 weeks","stack_with":[{"slug":"bpc-157","url":"https://www.peptide-wiki.net/peptides/bpc-157"},{"slug":"tb-500","url":"https://www.peptide-wiki.net/peptides/tb-500"}],"molecular":{"formula":"C49H79N17O14S","weight":null,"amino_acid_count":null,"cas_number":null,"pubchem_cid":null,"pubchem_url":null},"wada_banned":false,"wikipedia_url":null,"pricing":{"lowest_price_usd":59.99,"vendor_count":1,"in_stock_vendor_count":1,"vendors":[{"name":"PeptideTech","price_usd":59.99,"quantity_mg":12,"form":"injectable","in_stock":true,"buy_url":"https://peptidetech.co/?ref=bre&utm_source=affiliate","discount_code":"BRE"}]}},{"name":"BAM15","slug":"bam15","url":"https://www.peptide-wiki.net/peptides/bam15","aliases":["BAM 15","Mitochondrial Uncoupler BAM15"],"category":{"id":"e468247c-9d2d-4c47-8c72-623f273726e6","name":"Weight Management","slug":"weight-management"},"research_status":"research_only","research_status_label":"Research Use Only","administration_routes":["oral"],"half_life":"Unknown","summary":"A selective mitochondrial uncoupler that increases energy expenditure by diverting the proton gradient from ATP synthesis to heat production. In mouse models, BAM15 reversed diet-induced obesity and insulin resistance without increasing body temperature, heart rate, or affecting the plasma membrane — overcoming the critical safety limitations of earlier uncouplers like DNP.","mechanism":"BAM15 is a protonophoric compound that selectively permeabilizes the inner mitochondrial membrane to protons, uncoupling the electron transport chain from ATP synthase. This forces mitochondria to burn more fuel (fat) to maintain the membrane potential, dramatically increasing metabolic rate. Crucially, its bulky structure prevents it from crossing the plasma membrane, making it organ-selective and avoiding the hyperthermia that makes DNP dangerous.","benefits":["Reverses diet-induced obesity in mouse models","Increases resting metabolic rate without hyperthermia","Improves insulin sensitivity and glucose metabolism","Does not increase body temperature (unlike DNP)","No effect on heart rate at therapeutic doses","Prevents mitochondrial membrane-selective uncoupling","May have anti-cancer metabolic effects"],"side_effects":["Limited human data — primarily mouse models","Theoretical hyperthermia risk at high doses","GI discomfort possible","Not cleared for human use"],"dosage_info":{"unit":"mg/kg","notes":"Mouse studies used 5-20mg/kg. Human dose not established. Research compound only — significant caution warranted.","max_dose":20,"min_dose":5,"frequency":"Once daily oral","weight_based":true},"cycle_length":"4-8 weeks","stack_with":[{"slug":"mots-c","url":"https://www.peptide-wiki.net/peptides/mots-c"},{"slug":"aicar","url":"https://www.peptide-wiki.net/peptides/aicar"},{"slug":"slu-pp-332","url":"https://www.peptide-wiki.net/peptides/slu-pp-332"}],"molecular":{"formula":"C13H10F3N3O4S","weight":"357.4 Da","amino_acid_count":0,"cas_number":"1429651-50-2","pubchem_cid":null,"pubchem_url":null},"wada_banned":false,"wikipedia_url":null,"pricing":{"lowest_price_usd":125,"vendor_count":3,"in_stock_vendor_count":3,"vendors":[{"name":"Modified Aminos","price_usd":125,"quantity_mg":60,"form":"oral","in_stock":true,"buy_url":"https://modifiedaminos.shop/?ref=bre","discount_code":"BRE"},{"name":"PeptideTech","price_usd":148,"quantity_mg":60,"form":"oral","in_stock":true,"buy_url":"https://peptidetech.co/?ref=bre&utm_source=affiliate","discount_code":"BRE"},{"name":"Vandl Labs","price_usd":199.99,"quantity_mg":60,"form":"oral","in_stock":true,"buy_url":"https://vandl-labs.com/?ref=BRE","discount_code":"BRE"}]}},{"name":"BPC-157","slug":"bpc-157","url":"https://www.peptide-wiki.net/peptides/bpc-157","aliases":["Body Protection Compound-157","BPC157","Pentadecapeptide"],"category":{"id":"c74901aa-1014-4a30-ad71-de1c16e394b1","name":"Healing & Recovery","slug":"healing-recovery"},"research_status":"research_only","research_status_label":"Research Use Only","administration_routes":["subcutaneous injection","oral","topical"],"half_life":"4 hours (estimated)","summary":"A 15-amino acid peptide fragment derived from a protective protein found in gastric juice. Remarkably effective at accelerating healing of tendons, ligaments, muscles, and gut tissue.","mechanism":"BPC-157 promotes healing through multiple mechanisms: stimulating VEGF for angiogenesis, activating growth hormone receptors in tendon fibroblasts, and modulating the nitric oxide system.","benefits":["Accelerated tendon and ligament healing","Muscle repair and regeneration","Reduced inflammation","Gut health and intestinal healing","Liver protection and regeneration","Neuroprotection","Reduced pain at injury sites","Protection against NSAID-induced damage"],"side_effects":["Generally very well tolerated","Mild nausea (oral route)","Injection site discomfort","Theoretically may accelerate existing tumors (unconfirmed)"],"dosage_info":{"unit":"mcg/kg","notes":"Can be administered orally for gut issues. Typical daily dose: 200-500mcg total.","max_dose":10,"min_dose":1,"frequency":"Once or twice daily","weight_based":true},"cycle_length":"4-12 weeks","stack_with":[{"slug":"tb-500","url":"https://www.peptide-wiki.net/peptides/tb-500"},{"slug":"igf-1-lr3","url":"https://www.peptide-wiki.net/peptides/igf-1-lr3"},{"slug":"ghk-cu","url":"https://www.peptide-wiki.net/peptides/ghk-cu"}],"molecular":{"formula":"C62H98N16O22","weight":"1,419.5 Da","amino_acid_count":15,"cas_number":"137525-51-0","pubchem_cid":"9941957","pubchem_url":"https://pubchem.ncbi.nlm.nih.gov/compound/9941957"},"wada_banned":false,"wikipedia_url":"https://en.wikipedia.org/wiki/BPC-157","pricing":{"lowest_price_usd":24.99,"vendor_count":7,"in_stock_vendor_count":7,"vendors":[{"name":"PeptideTech","price_usd":24.99,"quantity_mg":5,"form":"injectable","in_stock":true,"buy_url":"https://peptidetech.co/?ref=bre&utm_source=affiliate","discount_code":"BRE"},{"name":"Modern Aminos","price_usd":34,"quantity_mg":5,"form":"injectable","in_stock":true,"buy_url":"https://modernaminos.com/?ref=bre","discount_code":"BRE"},{"name":"PeptideTech","price_usd":34.99,"quantity_mg":10,"form":"injectable","in_stock":true,"buy_url":"https://peptidetech.co/?ref=bre&utm_source=affiliate","discount_code":"BRE"},{"name":"Modified Aminos","price_usd":49.99,"quantity_mg":5,"form":"nasal_spray","in_stock":true,"buy_url":"https://modifiedaminos.shop/?ref=bre","discount_code":"BRE"},{"name":"FelixChem","price_usd":54.99,"quantity_mg":10,"form":"injectable","in_stock":true,"buy_url":"https://felixchem.is/refer/642/","discount_code":"Bre10"},{"name":"Modified Aminos","price_usd":79.99,"quantity_mg":30,"form":"oral","in_stock":true,"buy_url":"https://modifiedaminos.shop/?ref=bre","discount_code":"BRE"},{"name":"Vandl Labs","price_usd":89.99,"quantity_mg":30,"form":"oral","in_stock":true,"buy_url":"https://vandl-labs.com/?ref=BRE","discount_code":"BRE"}]}},{"name":"Bronchogen","slug":"bronchogen","url":"https://www.peptide-wiki.net/peptides/bronchogen","aliases":["Ala-Glu-Asp-Leu","Bronchial peptide bioregulator"],"category":{"id":"c74901aa-1014-4a30-ad71-de1c16e394b1","name":"Healing & Recovery","slug":"healing-recovery"},"research_status":"research_only","research_status_label":"Research Use Only","administration_routes":["subcutaneous injection"],"half_life":null,"summary":"A tetrapeptide (Ala-Glu-Asp-Leu) from the Khavinson bioregulator series specifically targeting bronchial and lung tissue. Studied for COPD, chronic bronchitis, and smoking-related lung damage. Normalizes bronchial epithelium proliferation and reduces respiratory inflammation.","mechanism":"Bronchogen penetrates bronchial epithelial cell nuclei and regulates gene expression in respiratory tissue. It inhibits excessive cell proliferation and inflammation while promoting repair of damaged bronchial mucosa. Anti-inflammatory effects mediated through NF-kB pathway suppression and reduced TNF-alpha and IL-6 production in lung tissue.","benefits":["Normalizes bronchial epithelium function","Anti-inflammatory in respiratory tissue","COPD and chronic bronchitis research","Promotes repair of smoking-damaged lung tissue","Reduces bronchial mucus hypersecretion","Anti-aging effects in lung tissue","May improve respiratory function in elderly patients"],"side_effects":["Generally well tolerated","Injection site reactions","Limited data outside Russian clinical research"],"dosage_info":{"unit":"mg","notes":"Standard Khavinson protocol: 1-2mg/day SubQ or IM for 10 days, 2x per year.","max_dose":2,"min_dose":1,"frequency":"Daily for 10-day courses","weight_based":false},"cycle_length":"10-day courses, 2x per year","stack_with":[{"slug":"thymosin-alpha-1","url":"https://www.peptide-wiki.net/peptides/thymosin-alpha-1"},{"slug":"kpv","url":"https://www.peptide-wiki.net/peptides/kpv"},{"slug":"vip","url":"https://www.peptide-wiki.net/peptides/vip"}],"molecular":{"formula":"C18H31N5O8","weight":"461.47 Da","amino_acid_count":4,"cas_number":null,"pubchem_cid":null,"pubchem_url":null},"wada_banned":false,"wikipedia_url":null,"pricing":{"lowest_price_usd":39.99,"vendor_count":1,"in_stock_vendor_count":1,"vendors":[{"name":"PeptideTech","price_usd":39.99,"quantity_mg":20,"form":"injectable","in_stock":true,"buy_url":"https://peptidetech.co/?ref=bre&utm_source=affiliate","discount_code":"BRE"}]}},{"name":"Cagrilintide","slug":"cagrilintide","url":"https://www.peptide-wiki.net/peptides/cagrilintide","aliases":["AM833","Long-acting amylin analog"],"category":{"id":"e468247c-9d2d-4c47-8c72-623f273726e6","name":"Weight Management","slug":"weight-management"},"research_status":"clinical_trials","research_status_label":"In Human Clinical Trials","administration_routes":["subcutaneous injection"],"half_life":"~7 days","summary":"A long-acting amylin analog being co-developed with semaglutide (as CagriSema) for obesity. Amylin signals satiety to the brain independently of GLP-1, making the combination synergistic for weight loss.","mechanism":"Cagrilintide activates amylin (calcitonin family) receptors in the brainstem and hypothalamus, signaling satiety and reducing food intake. When combined with semaglutide (CagriSema), the dual satiety mechanism produced 25.1% weight loss in Phase 3 trials — approaching the results of bariatric surgery.","benefits":["Signals satiety via amylin pathway — distinct from GLP-1","Combined with semaglutide: 25.1% weight loss (Phase 3)","Reduces food intake and increases feeling of fullness","Slows gastric emptying complementary to GLP-1","Potential for superior weight loss vs. tirzepatide"],"side_effects":["Nausea (especially when combined with semaglutide)","Vomiting","Constipation","Injection site reactions","Currently only in clinical trials"],"dosage_info":{"unit":"mg","notes":"Phase 3 trials use cagrilintide 2.4mg + semaglutide 2.4mg (CagriSema). Stand-alone dose being established.","max_dose":2.4,"min_dose":0.3,"frequency":"Once weekly subcutaneous injection","weight_based":false},"cycle_length":"Ongoing / chronic","stack_with":[{"slug":"semaglutide","url":"https://www.peptide-wiki.net/peptides/semaglutide"},{"slug":"tirzepatide","url":"https://www.peptide-wiki.net/peptides/tirzepatide"}],"molecular":{"formula":null,"weight":"4,850 Da","amino_acid_count":37,"cas_number":null,"pubchem_cid":"171397054","pubchem_url":"https://pubchem.ncbi.nlm.nih.gov/compound/171397054"},"wada_banned":false,"wikipedia_url":null,"pricing":{"lowest_price_usd":99.99,"vendor_count":2,"in_stock_vendor_count":2,"vendors":[{"name":"FelixChem","price_usd":99.99,"quantity_mg":5,"form":"injectable","in_stock":true,"buy_url":"https://felixchem.is/refer/642/","discount_code":"Bre10"},{"name":"FelixChem","price_usd":149.99,"quantity_mg":10,"form":"injectable","in_stock":true,"buy_url":"https://felixchem.is/refer/642/","discount_code":"Bre10"}]}},{"name":"Cardiogen","slug":"cardiogen","url":"https://www.peptide-wiki.net/peptides/cardiogen","aliases":["Heart peptide bioregulator","Ala-Glu-Asp-Gly cardiac"],"category":{"id":"c74901aa-1014-4a30-ad71-de1c16e394b1","name":"Healing & Recovery","slug":"healing-recovery"},"research_status":"research_only","research_status_label":"Research Use Only","administration_routes":["subcutaneous injection"],"half_life":null,"summary":"A tetrapeptide cardiac bioregulator from the Khavinson series targeting myocardial tissue. Normalizes myocardial cell function, reduces cardiac oxidative stress, and provides cardioprotection against ischemia and aging-related cardiac decline. Studied for heart failure, cardiomyopathy, and post-infarction recovery.","mechanism":"Cardiogen penetrates cardiomyocyte nuclei and regulates transcription of cardioprotective genes. It reduces lipid peroxidation in cardiac tissue, modulates calcium handling, and upregulates mitochondrial protective proteins. Unlike systemic cardiac drugs, Cardiogen's organ-targeting makes it selective for myocardial tissue with minimal off-target effects.","benefits":["Normalizes cardiomyocyte function","Cardioprotective against ischemia and reperfusion injury","Reduces cardiac oxidative stress","Anti-aging effects in myocardial tissue","Post-infarction recovery support","Reduces myocardial fibrosis","Arrhythmia-modulating properties in aging hearts"],"side_effects":["Generally well tolerated","Injection site reactions","Monitor cardiac function in heart disease patients"],"dosage_info":{"unit":"mg","notes":"Standard Khavinson protocol: 1-2mg/day for 10 days, 2x per year. Can combine with other Khavinson bioregulators.","max_dose":2,"min_dose":1,"frequency":"Daily for 10-day courses","weight_based":false},"cycle_length":"10-day courses, 2x per year","stack_with":[{"slug":"vesugen","url":"https://www.peptide-wiki.net/peptides/vesugen"},{"slug":"thymosin-alpha-1","url":"https://www.peptide-wiki.net/peptides/thymosin-alpha-1"},{"slug":"ss-31","url":"https://www.peptide-wiki.net/peptides/ss-31"}],"molecular":{"formula":null,"weight":"~450 Da","amino_acid_count":4,"cas_number":null,"pubchem_cid":null,"pubchem_url":null},"wada_banned":false,"wikipedia_url":null,"pricing":{"lowest_price_usd":49.99,"vendor_count":1,"in_stock_vendor_count":1,"vendors":[{"name":"PeptideTech","price_usd":49.99,"quantity_mg":20,"form":"injectable","in_stock":true,"buy_url":"https://peptidetech.co/?ref=bre&utm_source=affiliate","discount_code":"BRE"}]}},{"name":"Cartalax","slug":"cartalax","url":"https://www.peptide-wiki.net/peptides/cartalax","aliases":["Cartilage peptide bioregulator","AC-4 cartilage complex","Sigumir alternative"],"category":{"id":"c74901aa-1014-4a30-ad71-de1c16e394b1","name":"Healing & Recovery","slug":"healing-recovery"},"research_status":"research_only","research_status_label":"Research Use Only","administration_routes":["subcutaneous injection"],"half_life":null,"summary":"A cartilage and bone-targeting peptide bioregulator from the Khavinson series. Studied for arthritis, osteochondrosis, fracture recovery, and joint aging. Stimulates chondrocyte proliferation and collagen synthesis in cartilage tissue, supporting structural repair and maintenance of joint integrity.","mechanism":"Cartalax targets chondrocyte and osteoblast nuclei, regulating genes involved in extracellular matrix synthesis, collagen production, and proteoglycan synthesis. It promotes chondrocyte proliferation, inhibits MMP (matrix metalloproteinase) activity that degrades cartilage, and stimulates aggrecan and type-II collagen synthesis — the key components of healthy articular cartilage.","benefits":["Stimulates chondrocyte proliferation","Increases collagen type II and aggrecan synthesis","Inhibits cartilage-degrading MMPs","Fracture and cartilage injury recovery","Anti-aging effects in joints","Osteoarthritis and osteochondrosis research","Synergistic with BPC-157 for joint healing"],"side_effects":["Generally well tolerated","Injection site reactions","Limited Western clinical data"],"dosage_info":{"unit":"mg","notes":"Standard Khavinson protocol: 1-2mg/day for 10 days, 2x per year. Often combined with BPC-157 for comprehensive joint healing.","max_dose":2,"min_dose":1,"frequency":"Daily for 10-day courses","weight_based":false},"cycle_length":"10-day courses, 2x per year","stack_with":[{"slug":"bpc-157","url":"https://www.peptide-wiki.net/peptides/bpc-157"},{"slug":"tb-500","url":"https://www.peptide-wiki.net/peptides/tb-500"},{"slug":"ghk-cu","url":"https://www.peptide-wiki.net/peptides/ghk-cu"}],"molecular":{"formula":null,"weight":"~480 Da","amino_acid_count":4,"cas_number":null,"pubchem_cid":null,"pubchem_url":null},"wada_banned":false,"wikipedia_url":null,"pricing":{"lowest_price_usd":39.99,"vendor_count":1,"in_stock_vendor_count":1,"vendors":[{"name":"PeptideTech","price_usd":39.99,"quantity_mg":20,"form":"injectable","in_stock":true,"buy_url":"https://peptidetech.co/?ref=bre&utm_source=affiliate","discount_code":"BRE"}]}},{"name":"Cerebrolysin","slug":"cerebrolysin","url":"https://www.peptide-wiki.net/peptides/cerebrolysin","aliases":["FPF-1070"],"category":{"id":"e129dcd7-d24b-41f7-b43f-3355032b99eb","name":"Cognitive & Nootropic","slug":"cognitive"},"research_status":"prescription","research_status_label":"Prescription Only","administration_routes":["intramuscular injection","intravenous injection"],"half_life":null,"summary":"A complex mixture of low-molecular-weight neuropeptides derived from porcine brain proteins. The only peptide-based nootropic with robust clinical evidence for Alzheimer disease and brain injury.","mechanism":"Cerebrolysin contains neuropeptides that mimic endogenous neurotrophic factors (NGF, BDNF, CNTF, GDNF), promoting neurogenesis, synaptogenesis, and neurite growth.","benefits":["Demonstrated efficacy in Alzheimer disease trials","Stroke rehabilitation support","Traumatic brain injury recovery","Memory and cognitive improvement","Promotes neurogenesis","Neuroprotection"],"side_effects":["Headaches","Nausea and vomiting","Dizziness","Injection site pain","Rare allergic reactions"],"dosage_info":{"unit":"mL","notes":"Higher doses (20-30mL) used in clinical settings for brain injury.","max_dose":10,"min_dose":5,"frequency":"Daily intramuscular injection, 10-20 day courses","weight_based":false},"cycle_length":"10-20 days","stack_with":[{"slug":"semax","url":"https://www.peptide-wiki.net/peptides/semax"},{"slug":"epithalon","url":"https://www.peptide-wiki.net/peptides/epithalon"},{"slug":"noopept","url":"https://www.peptide-wiki.net/peptides/noopept"}],"molecular":{"formula":null,"weight":null,"amino_acid_count":null,"cas_number":null,"pubchem_cid":null,"pubchem_url":null},"wada_banned":false,"wikipedia_url":null,"pricing":{"lowest_price_usd":74.99,"vendor_count":1,"in_stock_vendor_count":1,"vendors":[{"name":"PeptideTech","price_usd":74.99,"quantity_mg":60,"form":"injectable","in_stock":true,"buy_url":"https://peptidetech.co/?ref=bre&utm_source=affiliate","discount_code":"BRE"}]}},{"name":"Chonluten","slug":"chonluten","url":"https://www.peptide-wiki.net/peptides/chonluten","aliases":["Bronchial mucosa bioregulator","Lung mucosa peptide","A-19 bioregulator"],"category":{"id":"c74901aa-1014-4a30-ad71-de1c16e394b1","name":"Healing & Recovery","slug":"healing-recovery"},"research_status":"research_only","research_status_label":"Research Use Only","administration_routes":["subcutaneous injection"],"half_life":null,"summary":"A peptide bioregulator targeting bronchial mucosa from the Khavinson series. Distinct from Bronchogen (which targets bronchial parenchyma), Chonluten specifically targets the mucous membrane lining of the bronchi. Studied for COPD, chronic mucus hypersecretion, and respiratory tract aging.","mechanism":"Chonluten penetrates bronchial mucosal epithelial cell nuclei and regulates genes involved in mucin synthesis, ciliary function, and mucosal immune defense. It normalizes goblet cell activity (reducing excess mucus), restores cilia motility, and reduces mucosal inflammation.","benefits":["Specifically targets bronchial mucous membrane","Normalizes mucus production in COPD and bronchitis","Restores cilia motility for airway clearance","Anti-inflammatory in respiratory mucosa","Distinct mechanism from Bronchogen (parenchymal focus)","Anti-aging effects in airway mucosa"],"side_effects":["Generally well tolerated","Injection site reactions","Limited data outside Russian research"],"dosage_info":{"unit":"mg","notes":"Standard Khavinson protocol: 1-2mg/day for 10 days, 2x per year. Can be combined with Bronchogen for comprehensive respiratory support.","max_dose":2,"min_dose":1,"frequency":"Daily for 10-day courses","weight_based":false},"cycle_length":"10-day courses, 2x per year","stack_with":[{"slug":"bronchogen","url":"https://www.peptide-wiki.net/peptides/bronchogen"},{"slug":"thymosin-alpha-1","url":"https://www.peptide-wiki.net/peptides/thymosin-alpha-1"},{"slug":"vip","url":"https://www.peptide-wiki.net/peptides/vip"}],"molecular":{"formula":null,"weight":"~450 Da","amino_acid_count":3,"cas_number":null,"pubchem_cid":null,"pubchem_url":null},"wada_banned":false,"wikipedia_url":null,"pricing":{"lowest_price_usd":39.99,"vendor_count":1,"in_stock_vendor_count":1,"vendors":[{"name":"PeptideTech","price_usd":39.99,"quantity_mg":20,"form":"injectable","in_stock":true,"buy_url":"https://peptidetech.co/?ref=bre&utm_source=affiliate","discount_code":"BRE"}]}},{"name":"CJC-1295","slug":"cjc-1295","url":"https://www.peptide-wiki.net/peptides/cjc-1295","aliases":["CJC-1295 DAC","Modified GRF 1-29","Mod GRF 1-29","CJC1295"],"category":{"id":"d2d9a29b-8c74-405c-91d8-d5223b400dd5","name":"Body Composition","slug":"body-composition"},"research_status":"research_only","research_status_label":"Research Use Only","administration_routes":["subcutaneous injection"],"half_life":"6-8 days (DAC)","summary":"A synthetic analog of growth hormone-releasing hormone (GHRH) that extends the half-life of endogenous GHRH. One of the most popular peptides for muscle growth and fat loss when stacked with a GHRP like Ipamorelin.","mechanism":"CJC-1295 is a 30-amino acid GHRH analog modified with a Drug Affinity Complex (DAC) to extend its half-life from minutes to days. It binds to GHRH receptors on the pituitary gland, stimulating pulsatile GH secretion and subsequently increasing IGF-1.","benefits":["Sustained elevation of GH and IGF-1 levels","Increased lean muscle mass","Enhanced fat metabolism and lipolysis","Improved recovery from training and injury","Better sleep quality and REM sleep","Improved skin elasticity and collagen synthesis","Potential anti-aging effects"],"side_effects":["Water retention","Mild fatigue","Headaches","Flushing","Joint pain at high doses","Potential insulin resistance with prolonged use"],"dosage_info":{"unit":"mcg","notes":"Non-DAC version dosed at 100-200mcg per injection, 1-3x daily.","max_dose":2000,"min_dose":1000,"frequency":"Once or twice weekly (DAC version)","weight_based":false},"cycle_length":"8-12 weeks","stack_with":[{"slug":"ipamorelin","url":"https://www.peptide-wiki.net/peptides/ipamorelin"},{"slug":"ghrp-6","url":"https://www.peptide-wiki.net/peptides/ghrp-6"},{"slug":"ghrp-2","url":"https://www.peptide-wiki.net/peptides/ghrp-2"}],"molecular":{"formula":"C152H252N44O42","weight":"3,647.25 Da","amino_acid_count":30,"cas_number":"863288-34-0","pubchem_cid":"91976842","pubchem_url":"https://pubchem.ncbi.nlm.nih.gov/compound/91976842"},"wada_banned":true,"wikipedia_url":"https://en.wikipedia.org/wiki/CJC-1295","pricing":{"lowest_price_usd":24,"vendor_count":2,"in_stock_vendor_count":2,"vendors":[{"name":"Modern Aminos","price_usd":24,"quantity_mg":2,"form":"injectable","in_stock":true,"buy_url":"https://modernaminos.com/?ref=bre","discount_code":"BRE"},{"name":"PeptideTech","price_usd":34.99,"quantity_mg":2,"form":"injectable","in_stock":true,"buy_url":"https://peptidetech.co/?ref=bre&utm_source=affiliate","discount_code":"BRE"}]}},{"name":"CJC-1295 No DAC (Mod GRF 1-29)","slug":"mod-grf-1-29","url":"https://www.peptide-wiki.net/peptides/mod-grf-1-29","aliases":["Modified GRF 1-29","CJC-1295 no DAC","Mod GRF","Sermorelin-like","GRF(1-29)"],"category":{"id":"d2d9a29b-8c74-405c-91d8-d5223b400dd5","name":"Body Composition","slug":"body-composition"},"research_status":"research_only","research_status_label":"Research Use Only","administration_routes":["subcutaneous injection"],"half_life":"30 minutes","summary":"A synthetic 29-amino acid GHRH analog with 4 amino acid substitutions that improve stability and receptor affinity compared to Sermorelin. Unlike CJC-1295 DAC, it has no Drug Affinity Complex, giving it a short 30-minute half-life that mimics the body's natural pulsatile GHRH secretion when co-administered with a GHRP.","mechanism":"Mod GRF 1-29 binds to GHRH receptors on pituitary somatotrophs and stimulates GH release in synchrony with an administered GHRP. Because of its short half-life, it produces a sharp, physiological GH pulse rather than the sustained elevation from CJC-1295 DAC. The 4 amino acid substitutions make it more stable than Sermorelin.","benefits":["Produces physiological pulsatile GH release","More stable than Sermorelin","Synergistic with any GHRP for 3-5x GH amplification","Flexible dosing schedule","Lower desensitization risk vs. DAC version","More affordable than DAC version"],"side_effects":["Very short half-life requires co-administration with GHRP","Must be dosed 1-3x daily (more injections)","Water retention","Mild headache"],"dosage_info":{"unit":"mcg","notes":"MUST be co-administered with a GHRP (Ipamorelin, GHRP-6, etc.) within 30 seconds for synergistic effect. Dose: 100-200mcg per injection.","max_dose":200,"min_dose":100,"frequency":"1-3x daily, always with a GHRP","weight_based":false},"cycle_length":"8-16 weeks","stack_with":[{"slug":"ipamorelin","url":"https://www.peptide-wiki.net/peptides/ipamorelin"},{"slug":"ghrp-6","url":"https://www.peptide-wiki.net/peptides/ghrp-6"},{"slug":"ghrp-2","url":"https://www.peptide-wiki.net/peptides/ghrp-2"}],"molecular":{"formula":"C152H252N44O42","weight":"3,367 Da","amino_acid_count":29,"cas_number":"863288-34-0","pubchem_cid":"863288","pubchem_url":"https://pubchem.ncbi.nlm.nih.gov/compound/863288"},"wada_banned":false,"wikipedia_url":null,"pricing":{"lowest_price_usd":39.95,"vendor_count":1,"in_stock_vendor_count":1,"vendors":[{"name":"PeptideTech","price_usd":39.95,"quantity_mg":5,"form":"injectable","in_stock":true,"buy_url":"https://peptidetech.co/?ref=bre&utm_source=affiliate","discount_code":"BRE"}]}},{"name":"Cortagen","slug":"cortagen","url":"https://www.peptide-wiki.net/peptides/cortagen","aliases":["Cerebral cortex peptide bioregulator","CNS tetrapeptide"],"category":{"id":"e129dcd7-d24b-41f7-b43f-3355032b99eb","name":"Cognitive & Nootropic","slug":"cognitive"},"research_status":"research_only","research_status_label":"Research Use Only","administration_routes":["subcutaneous injection"],"half_life":null,"summary":"A peptide bioregulator targeting the cerebral cortex and CNS from the Khavinson series. Normalizes cortical neuron function, reduces age-related neurodegeneration, and improves cognitive function. Particularly studied for age-associated cognitive decline, vascular dementia, and post-stroke recovery.","mechanism":"Cortagen targets cortical neuron nuclei and regulates expression of neuroprotective and neurotrophic genes. It reduces neuronal apoptosis under oxidative and ischemic stress, promotes synaptic plasticity, and normalizes neurotransmitter synthesis. Distinct from Pinealon (which targets pineal and circadian systems) in its direct cortical focus.","benefits":["Normalizes cortical neuron function","Reduces age-related cognitive decline","Neuroprotection under oxidative/ischemic stress","Post-stroke recovery support","Improves vascular dementia symptoms in Russian studies","Synaptic plasticity enhancement","Anti-aging effects in CNS"],"side_effects":["Generally well tolerated","Headache possible during initial use","Limited standalone Western clinical data"],"dosage_info":{"unit":"mg","notes":"Standard Khavinson protocol: 1-2mg/day for 10 days, 1-2x per year. Often combined with Semax or Pinealon.","max_dose":2,"min_dose":1,"frequency":"Daily for 10-day courses","weight_based":false},"cycle_length":"10-day courses, 1-2x per year","stack_with":[{"slug":"semax","url":"https://www.peptide-wiki.net/peptides/semax"},{"slug":"pinealon","url":"https://www.peptide-wiki.net/peptides/pinealon"},{"slug":"epithalon","url":"https://www.peptide-wiki.net/peptides/epithalon"}],"molecular":{"formula":null,"weight":"~460 Da","amino_acid_count":4,"cas_number":null,"pubchem_cid":null,"pubchem_url":null},"wada_banned":false,"wikipedia_url":null,"pricing":{"lowest_price_usd":49.99,"vendor_count":1,"in_stock_vendor_count":1,"vendors":[{"name":"PeptideTech","price_usd":49.99,"quantity_mg":20,"form":"injectable","in_stock":true,"buy_url":"https://peptidetech.co/?ref=bre&utm_source=affiliate","discount_code":"BRE"}]}},{"name":"Dihexa","slug":"dihexa","url":"https://www.peptide-wiki.net/peptides/dihexa","aliases":["PNB-0408","N-hexanoic-Tyr-Ile-(6) aminohexanoic amide"],"category":{"id":"e129dcd7-d24b-41f7-b43f-3355032b99eb","name":"Cognitive & Nootropic","slug":"cognitive"},"research_status":"research_only","research_status_label":"Research Use Only","administration_routes":["oral","sublingual"],"half_life":"Long (effects persist days)","summary":"An angiotensin IV-derived peptide that is reportedly millions of times more potent than BDNF at forming functional synaptic connections. Promotes dendritic spine growth via the HGF/c-Met signaling pathway. Researched for Alzheimer's disease, cognitive enhancement, and neuroplasticity.","mechanism":"Dihexa potentiates HGF (Hepatocyte Growth Factor) signaling through its c-Met receptor, which promotes dendritic spine formation and synaptic connectivity. Unlike BDNF which cannot cross the blood-brain barrier, Dihexa is orally bioavailable and crosses the BBB readily. It reverses cognitive deficits in models of Alzheimer's disease and aging.","benefits":["Dramatically increases synaptic connectivity (dendritic spine formation)","Orally bioavailable and crosses the blood-brain barrier","Reverses cognitive deficits in Alzheimer's models","Improves memory, learning, and cognitive performance","Acts via HGF/c-Met pathway — distinct from other nootropics","Long-lasting effects even after cessation"],"side_effects":["Potentially powerful psychostimulant effects","May be too stimulating for some users","Long-lasting neurological changes — effects persist after stopping","Limited human clinical data","Anxiety or overstimulation at high doses"],"dosage_info":{"unit":"mg","notes":"Highly potent — start with 5mg. Effects may persist for weeks after stopping. Do not combine with other pro-cognitive compounds carelessly.","max_dose":10,"min_dose":5,"frequency":"Once daily oral or sublingual","weight_based":false},"cycle_length":"2-4 weeks on, then assess","stack_with":[{"slug":"semax","url":"https://www.peptide-wiki.net/peptides/semax"},{"slug":"noopept","url":"https://www.peptide-wiki.net/peptides/noopept"}],"molecular":{"formula":"C21H33N3O4","weight":null,"amino_acid_count":null,"cas_number":null,"pubchem_cid":null,"pubchem_url":null},"wada_banned":false,"wikipedia_url":null,"pricing":{"lowest_price_usd":null,"vendor_count":0,"in_stock_vendor_count":0,"vendors":[]}},{"name":"DSIP","slug":"dsip","url":"https://www.peptide-wiki.net/peptides/dsip","aliases":["Delta Sleep Inducing Peptide"],"category":{"id":"e129dcd7-d24b-41f7-b43f-3355032b99eb","name":"Cognitive & Nootropic","slug":"cognitive"},"research_status":"research_only","research_status_label":"Research Use Only","administration_routes":["subcutaneous injection"],"half_life":null,"summary":"A neuropeptide that promotes slow-wave (delta wave) sleep and modulates stress hormones. Used for sleep optimization, stress reduction, and recovery enhancement.","mechanism":"DSIP induces slow-wave sleep by modulating serotonin, catecholamines, and GABA. It reduces cortisol and ACTH levels and modulates the stress response.","benefits":["Promotes deep delta wave sleep","Reduces cortisol and stress hormones","Improves sleep quality and duration","Antioxidant properties","Recovery enhancement"],"side_effects":["Mild headaches","Nausea","Generally well tolerated at low doses"],"dosage_info":{"unit":"mcg","notes":"Research compound with limited clinical data.","max_dose":500,"min_dose":100,"frequency":"Once daily, before sleep","weight_based":false},"cycle_length":"4-8 weeks","stack_with":[{"slug":"epithalon","url":"https://www.peptide-wiki.net/peptides/epithalon"},{"slug":"selank","url":"https://www.peptide-wiki.net/peptides/selank"}],"molecular":{"formula":"C35H48N10O15","weight":"848.9 Da","amino_acid_count":9,"cas_number":"62568-57-4","pubchem_cid":"68229","pubchem_url":"https://pubchem.ncbi.nlm.nih.gov/compound/68229"},"wada_banned":false,"wikipedia_url":"https://en.wikipedia.org/wiki/Delta_sleep-inducing_peptide","pricing":{"lowest_price_usd":34.99,"vendor_count":2,"in_stock_vendor_count":2,"vendors":[{"name":"Modified Aminos","price_usd":34.99,"quantity_mg":5,"form":"nasal_spray","in_stock":true,"buy_url":"https://modifiedaminos.shop/?ref=bre","discount_code":"BRE"},{"name":"FelixChem","price_usd":59.99,"quantity_mg":10,"form":"injectable","in_stock":true,"buy_url":"https://felixchem.is/refer/642/","discount_code":"Bre10"}]}},{"name":"Enclomiphene","slug":"enclomiphene","url":"https://www.peptide-wiki.net/peptides/enclomiphene","aliases":["Trans-clomiphene","Androxal","Enclomiphene citrate"],"category":{"id":"fa929c39-511d-485e-817d-30590e6f6e9a","name":"Sexual Health","slug":"sexual-health"},"research_status":"research_only","research_status_label":"Research Use Only","administration_routes":["oral"],"half_life":null,"summary":"The active trans-isomer of clomiphene citrate that acts as a selective estrogen receptor modulator (SERM). Blocks pituitary estrogen receptors to increase LH/FSH production and downstream testosterone synthesis. Studied for male hypogonadism as an alternative to TRT that preserves fertility and natural testosterone production.","mechanism":"Enclomiphene blocks estrogen receptors in the hypothalamus and pituitary, preventing negative feedback inhibition of GnRH, LH, and FSH secretion. This drives increased LH/FSH production, stimulating Leydig cells to produce more testosterone. Unlike exogenous testosterone, enclomiphene restores T through the natural HPG axis, preserving testicular function and fertility.","benefits":["Restores testosterone through natural HPG axis (preserves fertility)","Alternative to TRT for hypogonadism","Increases LH, FSH, and testosterone simultaneously","Preserves testicular size and sperm production","Once-daily oral administration","Does not suppress natural testosterone production long-term","May improve mood, energy, and libido"],"side_effects":["Mild estrogenic side effects possible (cis-isomer impurity)","Visual disturbances (rare, clomiphene class)","Hot flashes","Mood changes in some users"],"dosage_info":{"unit":"mg","notes":"Phase 3 dose: 12.5-25mg/day. Common research protocol: 12.5-25mg/day oral for 12 weeks. Monitor testosterone, LH, FSH, estradiol.","max_dose":25,"min_dose":12.5,"frequency":"Once daily oral","weight_based":false},"cycle_length":"12-24 weeks","stack_with":[{"slug":"gonadorelin","url":"https://www.peptide-wiki.net/peptides/gonadorelin"},{"slug":"kisspeptin-10","url":"https://www.peptide-wiki.net/peptides/kisspeptin-10"},{"slug":"testagen","url":"https://www.peptide-wiki.net/peptides/testagen"}],"molecular":{"formula":null,"weight":"405.9 Da","amino_acid_count":0,"cas_number":"15690-57-0","pubchem_cid":null,"pubchem_url":null},"wada_banned":false,"wikipedia_url":null,"pricing":{"lowest_price_usd":69.99,"vendor_count":2,"in_stock_vendor_count":2,"vendors":[{"name":"Modified Aminos","price_usd":69.99,"quantity_mg":1500,"form":"oral","in_stock":true,"buy_url":"https://modifiedaminos.shop/?ref=bre","discount_code":"BRE"},{"name":"Vandl Labs","price_usd":79.99,"quantity_mg":1500,"form":"oral","in_stock":true,"buy_url":"https://vandl-labs.com/?ref=BRE","discount_code":"BRE"}]}},{"name":"Endoluten","slug":"endoluten","url":"https://www.peptide-wiki.net/peptides/endoluten","aliases":["BioPineal","Pineal gland bioregulator","A-8 bioregulator"],"category":{"id":"ee678b1c-f2a5-4ab6-94fa-4d5f0dc4ee2b","name":"Anti-Aging & Longevity","slug":"anti-aging"},"research_status":"research_only","research_status_label":"Research Use Only","administration_routes":["oral","subcutaneous injection"],"half_life":null,"summary":"A natural pineal gland peptide bioregulator complex. Distinct from Epithalon (synthetic tetrapeptide) and Pinealon (synthetic tripeptide), Endoluten contains natural pineal peptide fractions that regulate melatonin production, circadian rhythms, and age-related neuroendocrine decline.","mechanism":"Endoluten contains natural pineal peptide fractions that normalize melatonin production by pinealocytes, regulate the hypothalamic-pituitary axis, and reduce free radical damage to pineal tissue. Unlike synthetic forms, the complex mixture targets multiple pineal functions simultaneously.","benefits":["Normalizes melatonin production","Regulates circadian rhythm disruption","Neuroendocrine anti-aging","Improves sleep architecture","Antioxidant effects in pineal tissue","Complements Epithalon for comprehensive anti-aging"],"side_effects":["May affect circadian timing if used incorrectly","Drowsiness if taken outside evening use"],"dosage_info":{"unit":"capsules","notes":"Available primarily as oral capsules (natural extract). Injectable forms exist. Evening use essential. Often combined with Epithalon.","max_dose":null,"min_dose":null,"frequency":"1-2 capsules before bedtime","weight_based":false},"cycle_length":"10-day courses, 2x per year","stack_with":[{"slug":"epithalon","url":"https://www.peptide-wiki.net/peptides/epithalon"},{"slug":"pinealon","url":"https://www.peptide-wiki.net/peptides/pinealon"},{"slug":"dsip","url":"https://www.peptide-wiki.net/peptides/dsip"}],"molecular":{"formula":null,"weight":"Variable (natural complex)","amino_acid_count":null,"cas_number":null,"pubchem_cid":null,"pubchem_url":null},"wada_banned":false,"wikipedia_url":null,"pricing":{"lowest_price_usd":55,"vendor_count":1,"in_stock_vendor_count":1,"vendors":[{"name":"PeptideTech","price_usd":55,"quantity_mg":20,"form":"oral","in_stock":true,"buy_url":"https://peptidetech.co/?ref=bre&utm_source=affiliate","discount_code":"BRE"}]}},{"name":"Epithalon","slug":"epithalon","url":"https://www.peptide-wiki.net/peptides/epithalon","aliases":["Epitalon","Epithalone","Ala-Glu-Asp-Gly"],"category":{"id":"ee678b1c-f2a5-4ab6-94fa-4d5f0dc4ee2b","name":"Anti-Aging & Longevity","slug":"anti-aging"},"research_status":"research_only","research_status_label":"Research Use Only","administration_routes":["subcutaneous injection","intramuscular injection","intranasal"],"half_life":null,"summary":"A synthetic tetrapeptide that activates telomerase, the enzyme responsible for lengthening telomeres. One of the only compounds with robust evidence for telomere extension in humans.","mechanism":"Epithalon stimulates the pineal gland to regulate melatonin, activates telomerase to maintain and extend telomere length, and modulates genes involved in aging and longevity.","benefits":["Activates telomerase and extends telomere length","Potential longevity effects","Improves sleep quality via melatonin regulation","Antioxidant properties","Immune function enhancement","Potential anti-cancer effects","Improved mood"],"side_effects":["Mild nausea","Stomach discomfort","Generally very well tolerated"],"dosage_info":{"unit":"mg","notes":"Typical cycle: 10-20 days, 1-2x per year.","max_dose":10,"min_dose":5,"frequency":"Once daily subcutaneous injection","weight_based":false},"cycle_length":"10-20 days, 1-2x per year","stack_with":[{"slug":"ghk-cu","url":"https://www.peptide-wiki.net/peptides/ghk-cu"},{"slug":"thymosin-alpha-1","url":"https://www.peptide-wiki.net/peptides/thymosin-alpha-1"},{"slug":"mots-c","url":"https://www.peptide-wiki.net/peptides/mots-c"}],"molecular":{"formula":"C14H22N4O9","weight":"390.35 Da","amino_acid_count":4,"cas_number":"307297-39-8","pubchem_cid":"219042","pubchem_url":"https://pubchem.ncbi.nlm.nih.gov/compound/219042"},"wada_banned":false,"wikipedia_url":"https://en.wikipedia.org/wiki/Epitalon","pricing":{"lowest_price_usd":34.99,"vendor_count":3,"in_stock_vendor_count":3,"vendors":[{"name":"PeptideTech","price_usd":34.99,"quantity_mg":10,"form":"injectable","in_stock":true,"buy_url":"https://peptidetech.co/?ref=bre&utm_source=affiliate","discount_code":"BRE"},{"name":"Modern Aminos","price_usd":44,"quantity_mg":10,"form":"injectable","in_stock":true,"buy_url":"https://modernaminos.com/?ref=bre","discount_code":"BRE"},{"name":"FelixChem","price_usd":129.99,"quantity_mg":50,"form":"injectable","in_stock":true,"buy_url":"https://felixchem.is/refer/642/","discount_code":"Bre10"}]}},{"name":"Follistatin-315","slug":"follistatin-315","url":"https://www.peptide-wiki.net/peptides/follistatin-315","aliases":["FST-315","Follistatin 315"],"category":{"id":"d2d9a29b-8c74-405c-91d8-d5223b400dd5","name":"Body Composition","slug":"body-composition"},"research_status":"research_only","research_status_label":"Research Use Only","administration_routes":["subcutaneous injection","intramuscular injection"],"half_life":null,"summary":"A truncated 315-amino acid isoform of follistatin that lacks the heparin-binding domain, giving it a shorter half-life and more localized action compared to Follistatin-344. Still potently inhibits myostatin and activin for muscle growth but with a different distribution profile.","mechanism":"Follistatin-315 binds and neutralizes myostatin and activin in tissues, removing the biological ceiling on muscle growth. The lack of a heparin-binding domain means it circulates more freely and has systemic distribution, while Follistatin-344 stays more localized near secretion sites.","benefits":["Inhibits myostatin for significant muscle mass increases","More systemic distribution than Follistatin-344","Increases lean body mass","Improves muscle recovery","Bone density enhancement"],"side_effects":["Limited long-term human safety data","Joint stress from rapid muscle growth","Injection site reactions","Potential hormonal effects via activin inhibition"],"dosage_info":{"unit":"mcg","notes":"Research cycles 10-30 days. Systemic distribution differs from FST-344. Very limited human data.","max_dose":100,"min_dose":50,"frequency":"Once daily","weight_based":false},"cycle_length":"10-30 days","stack_with":[{"slug":"igf-1-lr3","url":"https://www.peptide-wiki.net/peptides/igf-1-lr3"},{"slug":"cjc-1295","url":"https://www.peptide-wiki.net/peptides/cjc-1295"},{"slug":"follistatin-344","url":"https://www.peptide-wiki.net/peptides/follistatin-344"}],"molecular":{"formula":null,"weight":null,"amino_acid_count":null,"cas_number":null,"pubchem_cid":null,"pubchem_url":null},"wada_banned":true,"wikipedia_url":null,"pricing":{"lowest_price_usd":null,"vendor_count":0,"in_stock_vendor_count":0,"vendors":[]}},{"name":"Follistatin-344","slug":"follistatin-344","url":"https://www.peptide-wiki.net/peptides/follistatin-344","aliases":["FST-344"],"category":{"id":"d2d9a29b-8c74-405c-91d8-d5223b400dd5","name":"Body Composition","slug":"body-composition"},"research_status":"research_only","research_status_label":"Research Use Only","administration_routes":["subcutaneous injection","intramuscular injection"],"half_life":null,"summary":"A naturally occurring protein that inhibits myostatin and activin, effectively removing the biological ceiling on muscle growth.","mechanism":"Follistatin-344 is a 323-amino acid glycoprotein that acts as a natural myostatin inhibitor. By blocking myostatin, Follistatin-344 removes the genetic ceiling on muscle development.","benefits":["Removes myostatin-imposed ceiling on muscle growth","Dramatic increases in lean muscle mass","Increased bone density","Enhanced endurance","Anti-catabolic effects"],"side_effects":["Potential joint weakness","Injection site irritation","Elevated body temperature","Limited long-term human safety data"],"dosage_info":{"unit":"mcg","notes":"Research cycles of 10-30 days. Very limited human data.","max_dose":100,"min_dose":50,"frequency":"Once daily","weight_based":false},"cycle_length":"10-30 days","stack_with":[{"slug":"igf-1-lr3","url":"https://www.peptide-wiki.net/peptides/igf-1-lr3"},{"slug":"cjc-1295","url":"https://www.peptide-wiki.net/peptides/cjc-1295"}],"molecular":{"formula":null,"weight":"37,800 Da","amino_acid_count":344,"cas_number":"80449-31-6","pubchem_cid":null,"pubchem_url":null},"wada_banned":true,"wikipedia_url":"https://en.wikipedia.org/wiki/Follistatin","pricing":{"lowest_price_usd":99.99,"vendor_count":1,"in_stock_vendor_count":1,"vendors":[{"name":"PeptideTech","price_usd":99.99,"quantity_mg":1,"form":"injectable","in_stock":true,"buy_url":"https://peptidetech.co/?ref=bre&utm_source=affiliate","discount_code":"BRE"}]}},{"name":"FOXO4-DRI","slug":"foxo4-dri","url":"https://www.peptide-wiki.net/peptides/foxo4-dri","aliases":["FOXO4-D-Retro-Inverso","Senolytic peptide","FOXO4 peptide"],"category":{"id":"ee678b1c-f2a5-4ab6-94fa-4d5f0dc4ee2b","name":"Anti-Aging & Longevity","slug":"anti-aging"},"research_status":"research_only","research_status_label":"Research Use Only","administration_routes":["subcutaneous injection","intravenous injection"],"half_life":"Hours","summary":"A D-retro-inverso peptide that selectively induces apoptosis (programmed cell death) in senescent \"zombie\" cells. Based on a landmark 2017 Nature Medicine paper by van Deursen et al., it is one of the most targeted senolytic compounds under research.","mechanism":"Senescent cells (cells that have stopped dividing) accumulate with age and secrete inflammatory factors (SASP — senescence-associated secretory phenotype). FOXO4-DRI disrupts the interaction between the FOXO4 protein and p53, which senescent cells rely on to survive. This triggers apoptosis specifically in senescent cells while leaving healthy cells unaffected.","benefits":["Selectively destroys senescent (zombie) cells","Reduces SASP-driven chronic inflammation","May reverse age-related physical decline","Restores fitness, coat density, and renal function in aging mice","One of the most targeted senolytic agents known","Potential for cancer, organ fibrosis, and age-related disease"],"side_effects":["Limited human data — primarily mouse models","Potential immune response to cleared senescent cells","Must be cycled (not continuous) to allow system recovery","Transient inflammatory response as senescent cells are cleared"],"dosage_info":{"unit":"mg","notes":"Standard research protocol: 5-10mg subcutaneous for 3 days per week, monthly. Based on 2017 Nature Medicine study using 5mg/kg in mice. Human dose extrapolation is uncertain.","max_dose":10,"min_dose":5,"frequency":"3 consecutive days, then break","weight_based":false},"cycle_length":"3 days on, monthly cycles","stack_with":[{"slug":"epithalon","url":"https://www.peptide-wiki.net/peptides/epithalon"},{"slug":"ghk-cu","url":"https://www.peptide-wiki.net/peptides/ghk-cu"},{"slug":"mots-c","url":"https://www.peptide-wiki.net/peptides/mots-c"}],"molecular":{"formula":null,"weight":null,"amino_acid_count":null,"cas_number":null,"pubchem_cid":null,"pubchem_url":null},"wada_banned":false,"wikipedia_url":null,"pricing":{"lowest_price_usd":149.99,"vendor_count":1,"in_stock_vendor_count":1,"vendors":[{"name":"PeptideTech","price_usd":149.99,"quantity_mg":10,"form":"injectable","in_stock":true,"buy_url":"https://peptidetech.co/?ref=bre&utm_source=affiliate","discount_code":"BRE"}]}},{"name":"GHK-Cu","slug":"ghk-cu","url":"https://www.peptide-wiki.net/peptides/ghk-cu","aliases":["GHK-Copper","Copper Peptide","Copper Tripeptide-1"],"category":{"id":"ee678b1c-f2a5-4ab6-94fa-4d5f0dc4ee2b","name":"Anti-Aging & Longevity","slug":"anti-aging"},"research_status":"research_only","research_status_label":"Research Use Only","administration_routes":["topical","subcutaneous injection"],"half_life":null,"summary":"A naturally occurring copper-binding tripeptide that declines with age. Promotes skin rejuvenation, wound healing, hair growth, and anti-inflammatory effects. One of the most studied anti-aging peptides.","mechanism":"GHK-Cu activates copper-dependent enzymes for collagen and elastin synthesis, promotes wound healing via VEGF and FGF, activates stem cells in hair follicles, and resets aging-related gene expression patterns.","benefits":["Stimulates collagen and elastin production","Reduces fine lines and wrinkles","Accelerates wound healing","Promotes hair growth","Anti-inflammatory and antioxidant","Potential anti-cancer properties","Skin tightening and rejuvenation"],"side_effects":["Topical: mild skin irritation initially","Injectable: injection site reactions","Very well tolerated overall"],"dosage_info":{"unit":"mg","notes":"Available in topical creams/serums and injectable form.","max_dose":3,"min_dose":1,"frequency":"Daily topical or 1-3x per week injectable","weight_based":false},"cycle_length":"Ongoing","stack_with":[{"slug":"bpc-157","url":"https://www.peptide-wiki.net/peptides/bpc-157"},{"slug":"tb-500","url":"https://www.peptide-wiki.net/peptides/tb-500"},{"slug":"epithalon","url":"https://www.peptide-wiki.net/peptides/epithalon"}],"molecular":{"formula":"C14H24CuN6O4","weight":"403.92 Da (Cu complex)","amino_acid_count":3,"cas_number":"49557-75-7","pubchem_cid":"342538","pubchem_url":"https://pubchem.ncbi.nlm.nih.gov/compound/342538"},"wada_banned":false,"wikipedia_url":"https://en.wikipedia.org/wiki/Copper_peptide_GHK-Cu","pricing":{"lowest_price_usd":29.99,"vendor_count":6,"in_stock_vendor_count":6,"vendors":[{"name":"PeptideTech","price_usd":29.99,"quantity_mg":50,"form":"topical","in_stock":true,"buy_url":"https://peptidetech.co/?ref=bre&utm_source=affiliate","discount_code":"BRE"},{"name":"Modern Aminos","price_usd":34,"quantity_mg":50,"form":"topical","in_stock":true,"buy_url":"https://modernaminos.com/?ref=bre","discount_code":"BRE"},{"name":"Vandl Labs","price_usd":39.99,"quantity_mg":5,"form":"injectable","in_stock":true,"buy_url":"https://vandl-labs.com/?ref=BRE","discount_code":"BRE"},{"name":"FelixChem","price_usd":49.99,"quantity_mg":100,"form":"topical","in_stock":true,"buy_url":"https://felixchem.is/refer/642/","discount_code":"Bre10"},{"name":"Modified Aminos","price_usd":79.99,"quantity_mg":30,"form":"oral","in_stock":true,"buy_url":"https://modifiedaminos.shop/?ref=bre","discount_code":"BRE"},{"name":"Vandl Labs","price_usd":79.99,"quantity_mg":30,"form":"oral","in_stock":true,"buy_url":"https://vandl-labs.com/?ref=BRE","discount_code":"BRE"}]}},{"name":"GHRP-2","slug":"ghrp-2","url":"https://www.peptide-wiki.net/peptides/ghrp-2","aliases":["Growth Hormone Releasing Peptide-2","Pralmorelin"],"category":{"id":"d2d9a29b-8c74-405c-91d8-d5223b400dd5","name":"Body Composition","slug":"body-composition"},"research_status":"research_only","research_status_label":"Research Use Only","administration_routes":["subcutaneous injection"],"half_life":"15-60 minutes","summary":"A second-generation GHRP with high GH-releasing potency and a cleaner side effect profile than GHRP-6. Less appetite stimulation makes it preferable for body recomposition.","mechanism":"GHRP-2 is a synthetic hexapeptide that acts as a potent GHS-R agonist. It stimulates pulsatile GH release through both pituitary and hypothalamic mechanisms with less pronounced appetite stimulation than GHRP-6.","benefits":["Strong GH release with less cortisol elevation than GHRP-6","Muscle growth and recomposition","Fat loss","Minimal appetite stimulation","Improved recovery","IGF-1 increase"],"side_effects":["Cortisol and prolactin elevation (moderate)","Water retention","Headaches","Mild fatigue"],"dosage_info":{"unit":"mcg","notes":"Better choice than GHRP-6 when appetite stimulation is unwanted.","max_dose":300,"min_dose":100,"frequency":"1-3x daily","weight_based":false},"cycle_length":"8-12 weeks","stack_with":[{"slug":"cjc-1295","url":"https://www.peptide-wiki.net/peptides/cjc-1295"},{"slug":"sermorelin","url":"https://www.peptide-wiki.net/peptides/sermorelin"}],"molecular":{"formula":"C45H55N9O6","weight":"817.9 Da","amino_acid_count":6,"cas_number":"158861-67-7","pubchem_cid":"6918245","pubchem_url":"https://pubchem.ncbi.nlm.nih.gov/compound/6918245"},"wada_banned":true,"wikipedia_url":"https://en.wikipedia.org/wiki/GHRP-2","pricing":{"lowest_price_usd":29.99,"vendor_count":1,"in_stock_vendor_count":1,"vendors":[{"name":"PeptideTech","price_usd":29.99,"quantity_mg":10,"form":"injectable","in_stock":true,"buy_url":"https://peptidetech.co/?ref=bre&utm_source=affiliate","discount_code":"BRE"}]}},{"name":"GHRP-6","slug":"ghrp-6","url":"https://www.peptide-wiki.net/peptides/ghrp-6","aliases":["Growth Hormone Releasing Peptide-6","GHRP6"],"category":{"id":"d2d9a29b-8c74-405c-91d8-d5223b400dd5","name":"Body Composition","slug":"body-composition"},"research_status":"research_only","research_status_label":"Research Use Only","administration_routes":["subcutaneous injection","intranasal"],"half_life":"15-60 minutes","summary":"One of the first synthetic GHRPs developed, GHRP-6 is a potent GH secretagogue that also significantly stimulates appetite through ghrelin receptor activation.","mechanism":"GHRP-6 is a hexapeptide that acts on GHS-R receptors to stimulate GH release from the anterior pituitary. It also acts as a functional analog of ghrelin, significantly increasing appetite.","benefits":["Potent GH release","Significant increase in lean muscle mass","Enhanced recovery and tissue repair","Increased appetite (beneficial for hard gainers)","IGF-1 elevation","Anti-inflammatory properties"],"side_effects":["Strong hunger/appetite increase","Elevated cortisol and prolactin","Water retention","Lethargy","Potential desensitization"],"dosage_info":{"unit":"mcg","notes":"Stack with CJC-1295 for synergistic GH release.","max_dose":300,"min_dose":100,"frequency":"1-3x daily, 30-45 min before meals","weight_based":false},"cycle_length":"8-12 weeks","stack_with":[{"slug":"cjc-1295","url":"https://www.peptide-wiki.net/peptides/cjc-1295"}],"molecular":{"formula":"C46H56N12O6","weight":"872.44 Da","amino_acid_count":6,"cas_number":"87616-84-0","pubchem_cid":"72941687","pubchem_url":"https://pubchem.ncbi.nlm.nih.gov/compound/72941687"},"wada_banned":true,"wikipedia_url":"https://en.wikipedia.org/wiki/GHRP-6","pricing":{"lowest_price_usd":29.99,"vendor_count":1,"in_stock_vendor_count":1,"vendors":[{"name":"PeptideTech","price_usd":29.99,"quantity_mg":10,"form":"injectable","in_stock":true,"buy_url":"https://peptidetech.co/?ref=bre&utm_source=affiliate","discount_code":"BRE"}]}},{"name":"Glandokort","slug":"glandokort","url":"https://www.peptide-wiki.net/peptides/glandokort","aliases":["BioAdrenal","Adrenal gland bioregulator","A-17 bioregulator"],"category":{"id":"ee678b1c-f2a5-4ab6-94fa-4d5f0dc4ee2b","name":"Anti-Aging & Longevity","slug":"anti-aging"},"research_status":"research_only","research_status_label":"Research Use Only","administration_routes":["subcutaneous injection"],"half_life":null,"summary":"An adrenal gland-targeting peptide bioregulator. Normalizes adrenal cortex cell function and cortisol synthesis, reduces adrenal fatigue, and supports HPA axis recovery. Studied for HPA dysregulation, adrenal insufficiency, and stress-related aging.","mechanism":"Glandokort activates gene expression in adrenocortical cells regulating cortisol, DHEA, and aldosterone synthesis. It normalizes ACTH receptor sensitivity and reduces adrenal cell apoptosis under chronic stress, supporting cortisol rhythmicity.","benefits":["Normalizes adrenal cortex function","Reduces adrenal fatigue and HPA axis dysregulation","Supports cortisol rhythmicity","Increases DHEA production","Stress resilience support","Anti-aging effects on adrenal glands"],"side_effects":["Monitor cortisol and DHEA-S levels","Generally well tolerated","Injection site reactions"],"dosage_info":{"unit":"mg","notes":"Standard Khavinson protocol: 1-2mg/day for 10 days, 1-2x per year. Monitor AM cortisol, DHEA-S.","max_dose":2,"min_dose":1,"frequency":"Daily for 10-day courses","weight_based":false},"cycle_length":"10-day courses, 1-2x per year","stack_with":[{"slug":"epithalon","url":"https://www.peptide-wiki.net/peptides/epithalon"},{"slug":"thymalin","url":"https://www.peptide-wiki.net/peptides/thymalin"},{"slug":"dsip","url":"https://www.peptide-wiki.net/peptides/dsip"}],"molecular":{"formula":null,"weight":"~460 Da","amino_acid_count":4,"cas_number":null,"pubchem_cid":null,"pubchem_url":null},"wada_banned":false,"wikipedia_url":null,"pricing":{"lowest_price_usd":null,"vendor_count":0,"in_stock_vendor_count":0,"vendors":[]}},{"name":"GLP-2","slug":"glp-2","url":"https://www.peptide-wiki.net/peptides/glp-2","aliases":["Glucagon-Like Peptide-2","Teduglutide analog","GLP2"],"category":{"id":"c74901aa-1014-4a30-ad71-de1c16e394b1","name":"Healing & Recovery","slug":"healing-recovery"},"research_status":"research_only","research_status_label":"Research Use Only","administration_routes":["subcutaneous injection"],"half_life":"7 minutes (native); hours (teduglutide analog)","summary":"A 33-amino acid intestinal peptide secreted from L-cells of the gut that promotes intestinal mucosal growth, improves gut barrier function, and reduces inflammation. The FDA-approved analog Teduglutide (Gattex) is used for short bowel syndrome. GLP-2 research focuses on gut permeability, IBS/IBD, Crohn's disease, and gut-brain axis effects.","mechanism":"GLP-2 activates the GLP-2 receptor (GLP2R) on intestinal epithelial cells, subepithelial myofibroblasts, and enteric neurons. Receptor activation stimulates mucosal proliferation via IGF-1 and keratinocyte growth factor, inhibits apoptosis, and tightens intercellular junctions to reduce intestinal permeability. It also has anti-inflammatory effects via reduced pro-inflammatory cytokines and modulates gut motility.","benefits":["Promotes intestinal epithelial growth and repair","Reduces intestinal permeability (leaky gut)","Anti-inflammatory in GI tract","FDA-approved analog (Teduglutide) for short bowel syndrome","Reduces malabsorption and nutrient loss","May help IBD, Crohn's disease, and radiation enteritis","Gut-brain axis modulation"],"side_effects":["Nausea and vomiting","Abdominal pain","Injection site reactions","May stimulate intestinal neoplasm growth (monitor in cancer patients)","Fluid retention"],"dosage_info":{"unit":"mcg","notes":"Teduglutide (FDA-approved analog) dose: 0.05mg/kg once daily. Research GLP-2: 100-200mcg/day subcutaneous. Oral route largely ineffective due to enzymatic degradation.","max_dose":200,"min_dose":100,"frequency":"Once daily subcutaneous","weight_based":true},"cycle_length":"4-8 weeks","stack_with":[{"slug":"bpc-157","url":"https://www.peptide-wiki.net/peptides/bpc-157"},{"slug":"kpv","url":"https://www.peptide-wiki.net/peptides/kpv"},{"slug":"larazotide","url":"https://www.peptide-wiki.net/peptides/larazotide"}],"molecular":{"formula":"C146H226N40O43","weight":"3,957 Da","amino_acid_count":33,"cas_number":"116094-23-6","pubchem_cid":"16132300","pubchem_url":"https://pubchem.ncbi.nlm.nih.gov/compound/16132300"},"wada_banned":false,"wikipedia_url":"https://en.wikipedia.org/wiki/Glucagon-like_peptide-2","pricing":{"lowest_price_usd":65,"vendor_count":1,"in_stock_vendor_count":1,"vendors":[{"name":"PeptideTech","price_usd":65,"quantity_mg":5,"form":"injectable","in_stock":true,"buy_url":"https://peptidetech.co/?ref=bre&utm_source=affiliate","discount_code":"BRE"}]}},{"name":"Gonadorelin","slug":"gonadorelin","url":"https://www.peptide-wiki.net/peptides/gonadorelin","aliases":["GnRH","Gonadotropin-Releasing Hormone","LHRH","Factrel"],"category":{"id":"fa929c39-511d-485e-817d-30590e6f6e9a","name":"Sexual Health","slug":"sexual-health"},"research_status":"prescription","research_status_label":"Prescription Only","administration_routes":["subcutaneous injection"],"half_life":"2-4 minutes","summary":"A synthetic form of endogenous GnRH that stimulates the pituitary to release LH and FSH. Widely used in TRT protocols to maintain testicular size and function.","mechanism":"Gonadorelin binds GnRH receptors on pituitary gonadotroph cells, stimulating pulsatile release of LH and FSH, which drives testosterone production and spermatogenesis.","benefits":["Maintains testicular volume during TRT","Prevents secondary hypogonadism","Preserves fertility during testosterone use","Diagnostic tool for GnRH deficiency","Supports post-cycle recovery"],"side_effects":["Injection site reactions","Flushing","Nausea","Headache","Tachyphylaxis with continuous administration"],"dosage_info":{"unit":"mcg","notes":"Must be dosed pulsatilely (not continuously) to avoid desensitization.","max_dose":250,"min_dose":100,"frequency":"2-3x weekly, subcutaneous injection","weight_based":false},"cycle_length":"Concurrent with TRT","stack_with":[{"slug":"kisspeptin-10","url":"https://www.peptide-wiki.net/peptides/kisspeptin-10"},{"slug":"pt-141","url":"https://www.peptide-wiki.net/peptides/pt-141"}],"molecular":{"formula":"C55H75N17O13","weight":"1,182.3 Da","amino_acid_count":10,"cas_number":"33515-09-2","pubchem_cid":"638793","pubchem_url":"https://pubchem.ncbi.nlm.nih.gov/compound/638793"},"wada_banned":false,"wikipedia_url":"https://en.wikipedia.org/wiki/Gonadorelin","pricing":{"lowest_price_usd":29.99,"vendor_count":1,"in_stock_vendor_count":1,"vendors":[{"name":"PeptideTech","price_usd":29.99,"quantity_mg":2,"form":"injectable","in_stock":true,"buy_url":"https://peptidetech.co/?ref=bre&utm_source=affiliate","discount_code":"BRE"}]}},{"name":"Hexarelin","slug":"hexarelin","url":"https://www.peptide-wiki.net/peptides/hexarelin","aliases":["Examorelin","EP 23905"],"category":{"id":"d2d9a29b-8c74-405c-91d8-d5223b400dd5","name":"Body Composition","slug":"body-composition"},"research_status":"research_only","research_status_label":"Research Use Only","administration_routes":["subcutaneous injection"],"half_life":"30-70 minutes","summary":"A synthetic hexapeptide GHRP with the highest GH-releasing potency among the GHRP family. Notable for both its muscle-building effects and documented cardiovascular benefits.","mechanism":"Hexarelin is a 6-amino acid synthetic peptide that binds both the GHS-R receptor and the CD36 scavenger receptor. It stimulates strong GH release from the pituitary and has direct cardioprotective effects independent of GH secretion.","benefits":["Potent GH release (strongest among GHRPs)","Increased lean muscle mass and strength","Fat loss and body recomposition","Improved bone density","Enhanced collagen production","Direct cardioprotective effects","Accelerated healing"],"side_effects":["Elevated cortisol and prolactin","Fatigue and lethargy","Water retention","Potential insulin resistance","Desensitization with prolonged use","Headaches"],"dosage_info":{"unit":"mcg","notes":"Cycle 8-12 weeks then take a break to avoid desensitization.","max_dose":300,"min_dose":200,"frequency":"1-3x daily subcutaneous injection","weight_based":false},"cycle_length":"8-12 weeks","stack_with":[{"slug":"cjc-1295","url":"https://www.peptide-wiki.net/peptides/cjc-1295"},{"slug":"sermorelin","url":"https://www.peptide-wiki.net/peptides/sermorelin"}],"molecular":{"formula":"C47H58N12O6","weight":"887.04 Da","amino_acid_count":6,"cas_number":"140703-51-1","pubchem_cid":"6918297","pubchem_url":"https://pubchem.ncbi.nlm.nih.gov/compound/6918297"},"wada_banned":true,"wikipedia_url":"https://en.wikipedia.org/wiki/Hexarelin","pricing":{"lowest_price_usd":29.99,"vendor_count":1,"in_stock_vendor_count":1,"vendors":[{"name":"PeptideTech","price_usd":29.99,"quantity_mg":2,"form":"injectable","in_stock":true,"buy_url":"https://peptidetech.co/?ref=bre&utm_source=affiliate","discount_code":"BRE"}]}},{"name":"HGH Fragment 176-191","slug":"hgh-fragment-176-191","url":"https://www.peptide-wiki.net/peptides/hgh-fragment-176-191","aliases":["GH Fragment","HGH Frag 176-191","GH Frag 176-191"],"category":{"id":"e468247c-9d2d-4c47-8c72-623f273726e6","name":"Weight Management","slug":"weight-management"},"research_status":"research_only","research_status_label":"Research Use Only","administration_routes":["subcutaneous injection"],"half_life":"Short (~30 min)","summary":"The original C-terminal fragment of human growth hormone spanning amino acids 176-191. Contains the fat-burning region of HGH without the growth-promoting (IGF-1-stimulating) region. Slightly different structure from AOD-9604 but essentially the same compound; AOD-9604 is a modified version with a disulfide bridge.","mechanism":"HGH Fragment 176-191 directly mimics the lipolytic action of full HGH at the adipocyte level: it stimulates hormone-sensitive lipase (HSL) to break down stored fat (lipolysis) and suppresses the activity of lipoprotein lipase (LPL) which stores fat. Critically, it does not stimulate IGF-1, does not affect insulin, and does not promote long-bone growth.","benefits":["Pure fat-burning without growth or IGF-1 effects","Stimulates lipolysis (fat breakdown)","Inhibits lipogenesis (fat storage)","Cartilage healing properties also noted","No glucose dysregulation","Reduces obesity in multiple animal models"],"side_effects":["Minor headaches","Facial flushing","Injection site swelling","Low blood sugar if fasted (rare)"],"dosage_info":{"unit":"mcg","notes":"Best on empty stomach (enhances lipolytic effect). Morning fasted injection is most common. 6mg vial size typical.","max_dose":500,"min_dose":250,"frequency":"Once or twice daily, fasted state","weight_based":false},"cycle_length":"20-30 days","stack_with":[{"slug":"cjc-1295","url":"https://www.peptide-wiki.net/peptides/cjc-1295"},{"slug":"ipamorelin","url":"https://www.peptide-wiki.net/peptides/ipamorelin"},{"slug":"aod-9604","url":"https://www.peptide-wiki.net/peptides/aod-9604"}],"molecular":{"formula":"C78H123N23O23S2","weight":"1,817.0 Da","amino_acid_count":16,"cas_number":"66004-57-7","pubchem_cid":null,"pubchem_url":null},"wada_banned":false,"wikipedia_url":null,"pricing":{"lowest_price_usd":39.99,"vendor_count":1,"in_stock_vendor_count":1,"vendors":[{"name":"PeptideTech","price_usd":39.99,"quantity_mg":5,"form":"injectable","in_stock":true,"buy_url":"https://peptidetech.co/?ref=bre&utm_source=affiliate","discount_code":"BRE"}]}},{"name":"HMG","slug":"hmg","url":"https://www.peptide-wiki.net/peptides/hmg","aliases":["Human Menopausal Gonadotropin","Menopur","Menogon"],"category":{"id":"fa929c39-511d-485e-817d-30590e6f6e9a","name":"Sexual Health","slug":"sexual-health"},"research_status":"prescription","research_status_label":"Prescription Only","administration_routes":["subcutaneous injection","intramuscular injection"],"half_life":"24-36 hours","summary":"A urinary-derived combination of LH and FSH used clinically for fertility treatment and in TRT protocols for testicular stimulation and spermatogenesis support.","mechanism":"HMG contains both FSH and LH. LH stimulates Leydig cells to produce testosterone while FSH supports spermatogenesis and Sertoli cell function.","benefits":["Stimulates both testosterone production and spermatogenesis","Fertility support in men on TRT","Testicular volume maintenance","Combined LH and FSH activity","Superior to hCG for sperm production"],"side_effects":["Injection site reactions","Gynecomastia risk","Ovarian hyperstimulation in women","Mood changes"],"dosage_info":{"unit":"IU","notes":"Used in fertility medicine and TRT protocols. Requires medical supervision.","max_dose":150,"min_dose":75,"frequency":"3x weekly subcutaneous injection","weight_based":false},"cycle_length":"4-12 weeks","stack_with":[{"slug":"gonadorelin","url":"https://www.peptide-wiki.net/peptides/gonadorelin"},{"slug":"kisspeptin-10","url":"https://www.peptide-wiki.net/peptides/kisspeptin-10"}],"molecular":{"formula":null,"weight":null,"amino_acid_count":null,"cas_number":null,"pubchem_cid":null,"pubchem_url":null},"wada_banned":false,"wikipedia_url":null,"pricing":{"lowest_price_usd":39.99,"vendor_count":1,"in_stock_vendor_count":1,"vendors":[{"name":"PeptideTech","price_usd":39.99,"quantity_mg":75,"form":"injectable","in_stock":true,"buy_url":"https://peptidetech.co/?ref=bre&utm_source=affiliate","discount_code":"BRE"}]}},{"name":"Humanin","slug":"humanin","url":"https://www.peptide-wiki.net/peptides/humanin","aliases":["HN","mtDNA-encoded peptide","Humanin peptide"],"category":{"id":"ee678b1c-f2a5-4ab6-94fa-4d5f0dc4ee2b","name":"Anti-Aging & Longevity","slug":"anti-aging"},"research_status":"research_only","research_status_label":"Research Use Only","administration_routes":["subcutaneous injection","intramuscular injection"],"half_life":null,"summary":"A 21-amino acid mitochondria-derived peptide encoded in the 12S rRNA gene of the mitochondrial genome. The first discovered mitochondrial-derived peptide (MDP). Humanin protects neurons from Alzheimer-related toxicity, reduces cell death in multiple disease models, and has demonstrated significant anti-aging and longevity effects in animal studies.","mechanism":"Humanin is translated from the 16S rRNA region of the mitochondrial genome and activates multiple cytoprotective signaling pathways including JAK2/STAT3, MAPK, and PI3K/Akt. It blocks amyloid-beta toxicity, prevents apoptosis in neurons and cardiomyocytes, improves insulin sensitivity, reduces inflammation via STAT3/FOXO3, and modulates the IGF-1/growth hormone axis.","benefits":["Potent neuroprotection against amyloid-beta toxicity (Alzheimer research)","Anti-apoptotic in neurons, cardiomyocytes, and islet cells","Improves insulin sensitivity and metabolic function","Anti-aging and longevity: ~20% lifespan extension in animal models","Reduces atherosclerosis formation","Protects against chemotherapy-induced toxicity","Improves cognitive function in aging models","Reduces IGFBP-3 levels to enhance IGF-1 bioavailability"],"side_effects":["Limited human clinical data","Injection site reactions","Theoretical concern about pro-survival effects in cancer cells"],"dosage_info":{"unit":"mcg","notes":"Humanin and MOTS-C are the two best-studied mitochondrial-derived peptides (MDPs). Often used together. 100-500mcg/day or 5mg 3x/week studied in preclinical models.","max_dose":500,"min_dose":100,"frequency":"Daily to 3x weekly subcutaneous","weight_based":false},"cycle_length":"8-12 weeks","stack_with":[{"slug":"mots-c","url":"https://www.peptide-wiki.net/peptides/mots-c"},{"slug":"ss-31","url":"https://www.peptide-wiki.net/peptides/ss-31"},{"slug":"epithalon","url":"https://www.peptide-wiki.net/peptides/epithalon"}],"molecular":{"formula":"C115H179N37O34S2","weight":"2,803 Da","amino_acid_count":21,"cas_number":"313372-01-9","pubchem_cid":null,"pubchem_url":null},"wada_banned":true,"wikipedia_url":"https://en.wikipedia.org/wiki/Humanin","pricing":{"lowest_price_usd":null,"vendor_count":0,"in_stock_vendor_count":0,"vendors":[]}},{"name":"IGF-1 DES","slug":"igf-1-des","url":"https://www.peptide-wiki.net/peptides/igf-1-des","aliases":["Des(1-3)IGF-1","DES IGF-1","Truncated IGF-1","IGF-1 Des 1-3"],"category":{"id":"d2d9a29b-8c74-405c-91d8-d5223b400dd5","name":"Body Composition","slug":"body-composition"},"research_status":"research_only","research_status_label":"Research Use Only","administration_routes":["intramuscular injection"],"half_life":null,"summary":"A truncated analog of IGF-1 missing the first 3 amino acids from the N-terminus. This modification dramatically reduces its affinity for IGF-binding proteins (IGFBPs), making it approximately 10x more potent than native IGF-1 at the receptor level, with a much shorter half-life ideal for local/acute muscle actions.","mechanism":"IGF-1 DES lacks the IGFBP-binding domain found in native IGF-1, so nearly 100% of the administered dose reaches IGF-1R on target cells. This makes it extremely potent locally. When injected intramuscularly post-workout, it acts rapidly on satellite cells and muscle fibers at the injection site with minimal systemic spillover. Activates Akt/mTOR and MAPK pathways for protein synthesis.","benefits":["~10x more potent than native IGF-1 at receptor level","Local tissue action when injected IM (minimal systemic spillover)","Rapid satellite cell activation","Intense post-workout local muscle growth stimulus","Shorter half-life for precise timing","Works synergistically with IGF-1 LR3 (DES for acute local, LR3 for systemic)"],"side_effects":["Hypoglycemia risk (less than IGF-1 LR3 systemically but significant locally)","Extreme local swelling at injection site","Must pair with carbohydrates","Very short half-life means poor ROI from single injection"],"dosage_info":{"unit":"mcg","notes":"Inject directly into worked muscle groups immediately post-workout. Pair with carbohydrates. Short half-life makes timing critical. Typical dose: 50-150mcg per site.","max_dose":150,"min_dose":50,"frequency":"Immediately post-workout, IM injection into worked muscles","weight_based":false},"cycle_length":"2-4 weeks","stack_with":[{"slug":"igf-1-lr3","url":"https://www.peptide-wiki.net/peptides/igf-1-lr3"},{"slug":"mgf","url":"https://www.peptide-wiki.net/peptides/mgf"},{"slug":"peg-mgf","url":"https://www.peptide-wiki.net/peptides/peg-mgf"}],"molecular":{"formula":null,"weight":"~7,400 Da","amino_acid_count":67,"cas_number":null,"pubchem_cid":null,"pubchem_url":null},"wada_banned":true,"wikipedia_url":null,"pricing":{"lowest_price_usd":null,"vendor_count":0,"in_stock_vendor_count":0,"vendors":[]}},{"name":"IGF-1 LR3","slug":"igf-1-lr3","url":"https://www.peptide-wiki.net/peptides/igf-1-lr3","aliases":["IGF-1","Insulin-Like Growth Factor 1","Long R3 IGF-1"],"category":{"id":"d2d9a29b-8c74-405c-91d8-d5223b400dd5","name":"Body Composition","slug":"body-composition"},"research_status":"research_only","research_status_label":"Research Use Only","administration_routes":["subcutaneous injection","intramuscular injection"],"half_life":"20-30 hours","summary":"A long-acting analog of IGF-1 with a modified arginine substitution that extends its half-life. Directly stimulates muscle protein synthesis independent of GH.","mechanism":"IGF-1 LR3 is an 83-amino acid analog of endogenous IGF-1 that reduces its affinity for IGF-binding proteins, dramatically extending its half-life. It directly binds IGF-1 receptors in muscle and other tissues to stimulate protein synthesis.","benefits":["Direct muscle protein synthesis stimulation","Significant lean muscle mass increases","Enhanced fat oxidation","Improved nitrogen retention","Accelerated recovery from training","Anti-catabolic effects during caloric restriction"],"side_effects":["Hypoglycemia (most serious risk)","Stomach discomfort","Joint swelling","Jaw pain","Potential organ growth with excessive dosing","Water retention"],"dosage_info":{"unit":"mcg","notes":"Always administer with carbohydrates to prevent hypoglycemia.","max_dose":100,"min_dose":20,"frequency":"Once daily post-workout","weight_based":false},"cycle_length":"2-4 weeks","stack_with":[{"slug":"cjc-1295","url":"https://www.peptide-wiki.net/peptides/cjc-1295"},{"slug":"ipamorelin","url":"https://www.peptide-wiki.net/peptides/ipamorelin"},{"slug":"tb-500","url":"https://www.peptide-wiki.net/peptides/tb-500"}],"molecular":{"formula":"C400H625N111O115S9","weight":"9,117 Da","amino_acid_count":83,"cas_number":"946870-92-4","pubchem_cid":null,"pubchem_url":null},"wada_banned":true,"wikipedia_url":"https://en.wikipedia.org/wiki/IGF-1_LR3","pricing":{"lowest_price_usd":68,"vendor_count":2,"in_stock_vendor_count":2,"vendors":[{"name":"Modern Aminos","price_usd":68,"quantity_mg":1,"form":"injectable","in_stock":true,"buy_url":"https://modernaminos.com/?ref=bre","discount_code":"BRE"},{"name":"PeptideTech","price_usd":89.99,"quantity_mg":1,"form":"injectable","in_stock":true,"buy_url":"https://peptidetech.co/?ref=bre&utm_source=affiliate","discount_code":"BRE"}]}},{"name":"Ipamorelin","slug":"ipamorelin","url":"https://www.peptide-wiki.net/peptides/ipamorelin","aliases":["Ipamorelin acetate","NNC 26-0161"],"category":{"id":"d2d9a29b-8c74-405c-91d8-d5223b400dd5","name":"Body Composition","slug":"body-composition"},"research_status":"research_only","research_status_label":"Research Use Only","administration_routes":["subcutaneous injection"],"half_life":"2 hours","summary":"A selective growth hormone secretagogue and ghrelin mimetic that stimulates GH release without significantly elevating cortisol or prolactin. One of the cleanest and most widely used peptides for body recomposition.","mechanism":"Ipamorelin is a pentapeptide that selectively binds to the growth hormone secretagogue receptor (GHS-R), stimulating the pituitary gland to release growth hormone in a pulsatile, physiological manner. Unlike other GHRPs, it does not significantly elevate cortisol, prolactin, or ACTH, making it one of the most selective GH-releasing peptides available.","benefits":["Increases growth hormone and IGF-1 levels","Promotes lean muscle mass development","Supports fat loss and body recomposition","Improves sleep quality and recovery","Enhances bone density over time","Minimal cortisol or prolactin elevation compared to other GHRPs"],"side_effects":["Mild headaches (often from GH surge)","Water retention, especially early in use","Mild fatigue or lethargy","Potential numbness or tingling in extremities","Flushing at injection site"],"dosage_info":{"unit":"mcg","notes":"Commonly stacked with CJC-1295. 8-12 week cycles recommended.","max_dose":300,"min_dose":200,"frequency":"1-3x daily, ideally before bed or post-workout","weight_based":false},"cycle_length":"8-12 weeks","stack_with":[{"slug":"cjc-1295","url":"https://www.peptide-wiki.net/peptides/cjc-1295"},{"slug":"sermorelin","url":"https://www.peptide-wiki.net/peptides/sermorelin"}],"molecular":{"formula":"C38H49N9O5","weight":"711.9 Da","amino_acid_count":5,"cas_number":"170851-70-4","pubchem_cid":"9831659","pubchem_url":"https://pubchem.ncbi.nlm.nih.gov/compound/9831659"},"wada_banned":true,"wikipedia_url":"https://en.wikipedia.org/wiki/Ipamorelin","pricing":{"lowest_price_usd":34.99,"vendor_count":4,"in_stock_vendor_count":4,"vendors":[{"name":"PeptideTech","price_usd":34.99,"quantity_mg":5,"form":"injectable","in_stock":true,"buy_url":"https://peptidetech.co/?ref=bre&utm_source=affiliate","discount_code":"BRE"},{"name":"Modern Aminos","price_usd":38,"quantity_mg":5,"form":"injectable","in_stock":true,"buy_url":"https://modernaminos.com/?ref=bre","discount_code":"BRE"},{"name":"FelixChem","price_usd":49.99,"quantity_mg":10,"form":"injectable","in_stock":true,"buy_url":"https://felixchem.is/refer/642/","discount_code":"Bre10"},{"name":"PeptideTech","price_usd":59.99,"quantity_mg":10,"form":"injectable","in_stock":true,"buy_url":"https://peptidetech.co/?ref=bre&utm_source=affiliate","discount_code":"BRE"}]}},{"name":"Kisspeptin-10","slug":"kisspeptin-10","url":"https://www.peptide-wiki.net/peptides/kisspeptin-10","aliases":["Metastin 45-54","Kisspeptin 10","KP-10"],"category":{"id":"fa929c39-511d-485e-817d-30590e6f6e9a","name":"Sexual Health","slug":"sexual-health"},"research_status":"research_only","research_status_label":"Research Use Only","administration_routes":["subcutaneous injection","intranasal"],"half_life":"28 minutes","summary":"A 10-amino acid neuropeptide that acts as the master regulator of the reproductive hormonal axis by stimulating GnRH release. Supports testosterone, libido, fertility, and sexual health.","mechanism":"Kisspeptin-10 binds to KISS1R receptors on GnRH neurons in the hypothalamus, triggering pulsatile GnRH release which drives LH, FSH, testosterone, and estrogen production.","benefits":["Stimulates GnRH and downstream testosterone/estrogen","Increases sexual arousal and motivation","Supports fertility","Improves hormonal balance","Used in TRT protocols"],"side_effects":["Mild nausea","Headache","Flushing"],"dosage_info":{"unit":"mcg","notes":"Continuous administration can desensitize KISS1R. Use pulsatile dosing protocol.","max_dose":100,"min_dose":10,"frequency":"Pulse dosing 2-3x weekly","weight_based":false},"cycle_length":"4-8 weeks","stack_with":[{"slug":"pt-141","url":"https://www.peptide-wiki.net/peptides/pt-141"},{"slug":"gonadorelin","url":"https://www.peptide-wiki.net/peptides/gonadorelin"}],"molecular":{"formula":"C63H87N15O14","weight":"1,302.44 Da","amino_acid_count":10,"cas_number":"374675-21-5","pubchem_cid":"25240297","pubchem_url":"https://pubchem.ncbi.nlm.nih.gov/compound/25240297"},"wada_banned":false,"wikipedia_url":"https://en.wikipedia.org/wiki/Kisspeptin","pricing":{"lowest_price_usd":null,"vendor_count":0,"in_stock_vendor_count":0,"vendors":[]}},{"name":"KPV","slug":"kpv","url":"https://www.peptide-wiki.net/peptides/kpv","aliases":["Alpha-MSH(11-13)","Lys-Pro-Val","KPV tripeptide"],"category":{"id":"c74901aa-1014-4a30-ad71-de1c16e394b1","name":"Healing & Recovery","slug":"healing-recovery"},"research_status":"research_only","research_status_label":"Research Use Only","administration_routes":["oral","topical","subcutaneous injection"],"half_life":"~1 hour","summary":"A naturally occurring tripeptide (Lys-Pro-Val) derived from the C-terminus of alpha-MSH. Anti-inflammatory, antimicrobial, and gut-protective without causing skin pigmentation. Highly studied for IBD, Crohn's disease, skin conditions, and wound healing.","mechanism":"KPV acts on melanocortin receptors and directly inhibits NF-κB signaling to suppress inflammatory cytokines (IL-1β, IL-6, TNF-α). Unlike full alpha-MSH, it has no pigmentation effects (no MC1R binding) but retains all anti-inflammatory and antimicrobial properties. It also restores gut barrier function.","benefits":["Potent anti-inflammatory (inhibits NF-κB)","No pigmentation side effects","Gut barrier restoration and IBD research","Antimicrobial properties (Staphylococcus, Candida)","Wound healing acceleration","Skin condition treatment (psoriasis, eczema)","Effective orally and topically"],"side_effects":["Generally very well tolerated","Minimal reported side effects","Mild GI discomfort (rare)"],"dosage_info":{"unit":"mcg","notes":"Oral capsules effective for gut. Injectable for systemic effects. Topical for skin. Often combined with BPC-157 for gut protocols.","max_dose":500,"min_dose":250,"frequency":"1-2x daily oral, topical, or injectable","weight_based":false},"cycle_length":"4-8 weeks","stack_with":[{"slug":"bpc-157","url":"https://www.peptide-wiki.net/peptides/bpc-157"},{"slug":"ll-37","url":"https://www.peptide-wiki.net/peptides/ll-37"}],"molecular":{"formula":"C16H30N4O4","weight":null,"amino_acid_count":null,"cas_number":null,"pubchem_cid":null,"pubchem_url":null},"wada_banned":false,"wikipedia_url":null,"pricing":{"lowest_price_usd":39.99,"vendor_count":4,"in_stock_vendor_count":4,"vendors":[{"name":"PeptideTech","price_usd":39.99,"quantity_mg":10,"form":"injectable","in_stock":true,"buy_url":"https://peptidetech.co/?ref=bre&utm_source=affiliate","discount_code":"BRE"},{"name":"Modified Aminos","price_usd":74.99,"quantity_mg":30,"form":"oral","in_stock":true,"buy_url":"https://modifiedaminos.shop/?ref=bre","discount_code":"BRE"},{"name":"Vandl Labs","price_usd":74.99,"quantity_mg":30,"form":"oral","in_stock":true,"buy_url":"https://vandl-labs.com/?ref=BRE","discount_code":"BRE"},{"name":"FelixChem","price_usd":79.99,"quantity_mg":10,"form":"injectable","in_stock":true,"buy_url":"https://felixchem.is/refer/642/","discount_code":"Bre10"}]}},{"name":"L-Glutathione","slug":"l-glutathione","url":"https://www.peptide-wiki.net/peptides/l-glutathione","aliases":["GSH","Reduced glutathione","gamma-L-Glutamyl-L-cysteinyl-glycine"],"category":{"id":"ee678b1c-f2a5-4ab6-94fa-4d5f0dc4ee2b","name":"Anti-Aging & Longevity","slug":"anti-aging"},"research_status":"research_only","research_status_label":"Research Use Only","administration_routes":["intravenous injection","subcutaneous injection","oral"],"half_life":null,"summary":"The body's master antioxidant and a tripeptide (Glu-Cys-Gly) found in virtually every cell. Injectable and IV glutathione dramatically raises systemic levels for anti-aging, skin brightening, neuroprotection, liver detoxification, and chronic disease management. Oral bioavailability is poor; injectable forms bypass absorption limitations.","mechanism":"Glutathione neutralizes reactive oxygen species (ROS) directly, regenerates vitamins C and E, and is required for Phase II hepatic detoxification via glutathione-S-transferase (GST). It also protects mitochondria, reduces inflammation via NF-kB pathway, and inhibits melanin synthesis (skin brightening mechanism). Direct injection bypasses the poor oral absorption that limits oral glutathione supplementation.","benefits":["Potent master antioxidant neutralizing ROS and free radicals","Liver detoxification (Phase II conjugation)","Skin brightening via melanin synthesis inhibition","Neuroprotection in Parkinson disease models","Immune system enhancement","Anti-aging via mitochondrial protection","Heavy metal chelation","Reduces oxidative stress in chronic disease"],"side_effects":["IV: flushing nausea if infused too rapidly","High doses may cause zinc depletion","Oral form largely ineffective (use sublingual or liposomal)"],"dosage_info":{"unit":"mg","notes":"IV drip: 600-2400mg in 100-250mL saline over 30-60 min. SubQ: 600mg 3x/week. Oral liposomal: 250-500mg daily.","max_dose":2400,"min_dose":600,"frequency":"2-3x per week IV or daily SubQ","weight_based":false},"cycle_length":"Ongoing","stack_with":[{"slug":"nad-plus","url":"https://www.peptide-wiki.net/peptides/nad-plus"},{"slug":"epithalon","url":"https://www.peptide-wiki.net/peptides/epithalon"},{"slug":"thymosin-alpha-1","url":"https://www.peptide-wiki.net/peptides/thymosin-alpha-1"}],"molecular":{"formula":"C10H17N3O6S","weight":"307.32 Da","amino_acid_count":3,"cas_number":"70-18-8","pubchem_cid":"124886","pubchem_url":"https://pubchem.ncbi.nlm.nih.gov/compound/124886"},"wada_banned":false,"wikipedia_url":"https://en.wikipedia.org/wiki/Glutathione","pricing":{"lowest_price_usd":29.99,"vendor_count":3,"in_stock_vendor_count":3,"vendors":[{"name":"PeptideTech","price_usd":29.99,"quantity_mg":200,"form":"injectable","in_stock":true,"buy_url":"https://peptidetech.co/?ref=bre&utm_source=affiliate","discount_code":"BRE"},{"name":"Modified Aminos","price_usd":44.99,"quantity_mg":500,"form":"nasal_spray","in_stock":true,"buy_url":"https://modifiedaminos.shop/?ref=bre","discount_code":"BRE"},{"name":"FelixChem","price_usd":69.99,"quantity_mg":30,"form":"injectable","in_stock":true,"buy_url":"https://felixchem.is/refer/642/","discount_code":"Bre10"}]}},{"name":"Larazotide","slug":"larazotide","url":"https://www.peptide-wiki.net/peptides/larazotide","aliases":["AT-1001","Larazotide acetate"],"category":{"id":"c74901aa-1014-4a30-ad71-de1c16e394b1","name":"Healing & Recovery","slug":"healing-recovery"},"research_status":"clinical_trials","research_status_label":"In Human Clinical Trials","administration_routes":["oral"],"half_life":"Short (~1 hour)","summary":"An 8-amino acid synthetic peptide designed to regulate tight junctions between intestinal epithelial cells. Directly targets intestinal permeability (leaky gut) and is the only compound in clinical trials specifically for tight junction regulation in celiac disease.","mechanism":"Larazotide mimics the action of a naturally-occurring tight junction regulator, blocking zonulin signaling which normally opens intestinal tight junctions. By keeping tight junctions closed, it prevents luminal antigens and bacteria from crossing the gut barrier into systemic circulation — addressing the root mechanism of leaky gut.","benefits":["Reduces intestinal permeability (leaky gut)","Specifically targets tight junction regulation","In Phase 2/3 clinical trials for celiac disease","Reduces gluten-induced symptoms in celiac patients","May help IBD, IBS, and food sensitivities","Gut barrier integrity restoration"],"side_effects":["Generally well tolerated in clinical trials","Mild nausea (rare)","Headache (reported in trials)"],"dosage_info":{"unit":"mcg","notes":"Clinical trials used 0.5mg-2mg three times daily before meals. Most research uses 500mcg-1mg TID.","max_dose":2000,"min_dose":250,"frequency":"3x daily, 30 min before meals","weight_based":false},"cycle_length":"6-12 weeks","stack_with":[{"slug":"bpc-157","url":"https://www.peptide-wiki.net/peptides/bpc-157"},{"slug":"kpv","url":"https://www.peptide-wiki.net/peptides/kpv"}],"molecular":{"formula":"C32H60N12O12S2","weight":"792.9 Da","amino_acid_count":8,"cas_number":"1401028-24-7","pubchem_cid":"44146842","pubchem_url":"https://pubchem.ncbi.nlm.nih.gov/compound/44146842"},"wada_banned":false,"wikipedia_url":"https://en.wikipedia.org/wiki/Larazotide","pricing":{"lowest_price_usd":65,"vendor_count":1,"in_stock_vendor_count":1,"vendors":[{"name":"PeptideTech","price_usd":65,"quantity_mg":30,"form":"oral","in_stock":true,"buy_url":"https://peptidetech.co/?ref=bre&utm_source=affiliate","discount_code":"BRE"}]}},{"name":"Liraglutide","slug":"liraglutide","url":"https://www.peptide-wiki.net/peptides/liraglutide","aliases":["Victoza","Saxenda"],"category":{"id":"e468247c-9d2d-4c47-8c72-623f273726e6","name":"Weight Management","slug":"weight-management"},"research_status":"fda_approved","research_status_label":"FDA Approved","administration_routes":["subcutaneous injection"],"half_life":"13 hours","summary":"An FDA-approved once-daily GLP-1 receptor agonist for type 2 diabetes and weight management. Produces 5-8% average weight loss with established cardiovascular safety data.","mechanism":"Liraglutide is a 97% homologous GLP-1 analog with a fatty acid side chain that enables once-daily dosing. It activates GLP-1 receptors to slow gastric emptying and reduce appetite.","benefits":["FDA-approved for weight management","Reduces appetite and caloric intake","5-8% average weight reduction","Improved glycemic control","Cardiovascular safety established","Once-daily dosing"],"side_effects":["Nausea (very common)","Diarrhea","Constipation","Vomiting","Injection site reactions","Potential gallbladder disease"],"dosage_info":{"unit":"mg","notes":"Start at 0.6mg/day, titrate weekly to target of 1.8mg or 3mg.","max_dose":3,"min_dose":0.6,"frequency":"Once daily subcutaneous injection","weight_based":false},"cycle_length":"Ongoing / chronic","stack_with":[],"molecular":{"formula":"C172H265N43O51","weight":"3,751 Da","amino_acid_count":31,"cas_number":"204656-20-2","pubchem_cid":"16134956","pubchem_url":"https://pubchem.ncbi.nlm.nih.gov/compound/16134956"},"wada_banned":false,"wikipedia_url":"https://en.wikipedia.org/wiki/Liraglutide","pricing":{"lowest_price_usd":48,"vendor_count":1,"in_stock_vendor_count":1,"vendors":[{"name":"Modern Aminos","price_usd":48,"quantity_mg":5,"form":"injectable","in_stock":true,"buy_url":"https://modernaminos.com/?ref=bre","discount_code":"BRE"}]}},{"name":"Livagen","slug":"livagen","url":"https://www.peptide-wiki.net/peptides/livagen","aliases":["KEDA tetrapeptide","Lys-Glu-Asp-Ala","Liver peptide bioregulator"],"category":{"id":"ee678b1c-f2a5-4ab6-94fa-4d5f0dc4ee2b","name":"Anti-Aging & Longevity","slug":"anti-aging"},"research_status":"research_only","research_status_label":"Research Use Only","administration_routes":["subcutaneous injection"],"half_life":null,"summary":"A synthetic tetrapeptide (Lys-Glu-Asp-Ala) from the Khavinson bioregulator series that de-heterochromatinizes age-condensed chromatin in lymphocytes, restoring youthful gene expression patterns. Hepatoprotective and immunomodulatory. One of the most mechanistically unique anti-aging peptides — it directly reactivates genes silenced by chromatin condensation with age.","mechanism":"Livagen penetrates cell nuclei and binds to condensed chromatin regions (heterochromatin) that have been silenced with aging, particularly histone H1-DNA interactions. This de-condensation reactivates ribosomal genes and other age-silenced transcriptional programs. In human lymphocyte cultures, Livagen restores ribosomal RNA synthesis rates to youthful levels within 24 hours. Also has hepatoprotective effects via anti-apoptotic signaling in liver cells.","benefits":["Unique mechanism: directly de-condenses age-silenced chromatin","Reactivates ribosomal genes and silenced transcription","Restores youthful gene expression in lymphocytes","Hepatoprotective and anti-apoptotic in liver","Immunomodulatory via lymphocyte activation","Anti-aging at the fundamental epigenetic level","Synergistic with other anti-aging peptide bioregulators"],"side_effects":["Limited standalone clinical data beyond Russian research","Well tolerated in available studies","Injection site reactions"],"dosage_info":{"unit":"mg","notes":"Standard Khavinson protocol: 1-2mg/day subcutaneous or IM for 10 days, 1-2x per year.","max_dose":2,"min_dose":1,"frequency":"Daily injection for 10-day courses","weight_based":false},"cycle_length":"10-day courses, 1-2x per year","stack_with":[{"slug":"epithalon","url":"https://www.peptide-wiki.net/peptides/epithalon"},{"slug":"ghk-cu","url":"https://www.peptide-wiki.net/peptides/ghk-cu"},{"slug":"vesugen","url":"https://www.peptide-wiki.net/peptides/vesugen"}],"molecular":{"formula":"C18H33N5O7","weight":"447.49 Da","amino_acid_count":4,"cas_number":"137562-23-3","pubchem_cid":null,"pubchem_url":null},"wada_banned":false,"wikipedia_url":null,"pricing":{"lowest_price_usd":null,"vendor_count":0,"in_stock_vendor_count":0,"vendors":[]}},{"name":"LL-37","slug":"ll-37","url":"https://www.peptide-wiki.net/peptides/ll-37","aliases":["Cathelicidin","hCAP18/LL-37","CAMP"],"category":{"id":"56c716fd-7ce4-4ac1-86e5-c8c1ff11351e","name":"Immune Support","slug":"immune-support"},"research_status":"research_only","research_status_label":"Research Use Only","administration_routes":["subcutaneous injection","topical"],"half_life":null,"summary":"The only human cathelicidin antimicrobial peptide, naturally produced by immune cells as a first-line defense. Has broad-spectrum antimicrobial, wound healing, and immunomodulatory properties.","mechanism":"LL-37 disrupts bacterial, fungal, and viral cell membranes through direct membrane permeabilization and acts as an immunomodulator by binding TLR receptors.","benefits":["Broad-spectrum antimicrobial","Innate immune defense","Wound healing acceleration","Anti-inflammatory in chronic conditions","Potential anti-tumor properties"],"side_effects":["Injection site irritation","Limited long-term human data","Paradoxically pro-inflammatory in some contexts"],"dosage_info":{"unit":"mcg","notes":"Research compound. Topical formulations used for skin infections.","max_dose":500,"min_dose":100,"frequency":"Daily to 3x weekly","weight_based":false},"cycle_length":"4-8 weeks","stack_with":[{"slug":"thymosin-alpha-1","url":"https://www.peptide-wiki.net/peptides/thymosin-alpha-1"},{"slug":"bpc-157","url":"https://www.peptide-wiki.net/peptides/bpc-157"}],"molecular":{"formula":null,"weight":null,"amino_acid_count":null,"cas_number":null,"pubchem_cid":null,"pubchem_url":null},"wada_banned":false,"wikipedia_url":null,"pricing":{"lowest_price_usd":49.99,"vendor_count":1,"in_stock_vendor_count":1,"vendors":[{"name":"PeptideTech","price_usd":49.99,"quantity_mg":10,"form":"injectable","in_stock":true,"buy_url":"https://peptidetech.co/?ref=bre&utm_source=affiliate","discount_code":"BRE"}]}},{"name":"Macimorelin","slug":"macimorelin","url":"https://www.peptide-wiki.net/peptides/macimorelin","aliases":["AEZS-130","Macrilen"],"category":{"id":"331638a6-1066-49e5-9186-33cfc08ae05d","name":"Experimental","slug":"experimental"},"research_status":"fda_approved","research_status_label":"FDA Approved","administration_routes":["oral"],"half_life":"4 hours","summary":"An orally active ghrelin receptor agonist FDA-approved as a diagnostic test for adult growth hormone deficiency. Provides a convenient oral GH stimulation test.","mechanism":"Macimorelin activates ghrelin receptors (GHS-R1a) in the pituitary, stimulating GH release. FDA-approved specifically for diagnosing GH deficiency in adults.","benefits":["FDA-approved diagnostic for adult GH deficiency","Oral administration for testing","Reliable GH stimulation","Investigated for therapeutic GH deficiency treatment"],"side_effects":["Nausea","Headache","Dysgeusia (taste disturbance)","Dizziness","Fatigue"],"dosage_info":{"unit":"mg/kg","notes":"Diagnostic dose: 0.5mg/kg oral, single administration.","max_dose":0.5,"min_dose":0.5,"frequency":"Single dose (diagnostic use)","weight_based":true},"cycle_length":"Single dose (diagnostic)","stack_with":[],"molecular":{"formula":"C26H29FN4O3","weight":null,"amino_acid_count":null,"cas_number":null,"pubchem_cid":null,"pubchem_url":null},"wada_banned":false,"wikipedia_url":null,"pricing":{"lowest_price_usd":89.99,"vendor_count":1,"in_stock_vendor_count":1,"vendors":[{"name":"PeptideTech","price_usd":89.99,"quantity_mg":10,"form":"oral","in_stock":true,"buy_url":"https://peptidetech.co/?ref=bre&utm_source=affiliate","discount_code":"BRE"}]}},{"name":"Mazdutide","slug":"mazdutide","url":"https://www.peptide-wiki.net/peptides/mazdutide","aliases":["Peptide-M","IBI362","GLP-1/Gcg receptor agonist"],"category":{"id":"e468247c-9d2d-4c47-8c72-623f273726e6","name":"Weight Management","slug":"weight-management"},"research_status":"clinical_trials","research_status_label":"In Human Clinical Trials","administration_routes":["subcutaneous injection"],"half_life":null,"summary":"A GLP-1 and glucagon receptor co-agonist developed by Innovent Biologics. In Phase 3 clinical trials in China with strong efficacy data. Shows comparable weight loss to tirzepatide while also reducing liver fat. Also studied for type 2 diabetes management.","mechanism":"Mazdutide activates both GLP-1R and glucagon receptor with a balanced agonism ratio. GLP-1R activation drives appetite suppression and glucose control; glucagon receptor activation increases resting energy expenditure and promotes hepatic lipid oxidation. Together these pathways produce robust weight loss with additional metabolic benefits.","benefits":["Robust weight loss: 12-15% body weight in Phase 3 trials","Dual GLP-1 and glucagon receptor activation","Significant reduction in liver fat (NASH application)","Glucose control improvement","Once-weekly dosing","Strong Phase 3 data from Chinese clinical trials"],"side_effects":["Nausea and vomiting","GI side effects typical of GLP-1 class","Phase 3 data primarily from Chinese population"],"dosage_info":{"unit":"mg","notes":"Phase 3 doses used: 3-9mg/week. Titration protocol recommended. Not yet FDA approved.","max_dose":6,"min_dose":2,"frequency":"Once weekly subcutaneous injection","weight_based":false},"cycle_length":"Ongoing / chronic","stack_with":[{"slug":"tirzepatide","url":"https://www.peptide-wiki.net/peptides/tirzepatide"},{"slug":"retatrutide","url":"https://www.peptide-wiki.net/peptides/retatrutide"},{"slug":"survodutide","url":"https://www.peptide-wiki.net/peptides/survodutide"}],"molecular":{"formula":null,"weight":"~4,700 Da","amino_acid_count":null,"cas_number":null,"pubchem_cid":null,"pubchem_url":null},"wada_banned":false,"wikipedia_url":null,"pricing":{"lowest_price_usd":249.99,"vendor_count":1,"in_stock_vendor_count":1,"vendors":[{"name":"FelixChem","price_usd":249.99,"quantity_mg":15,"form":"injectable","in_stock":true,"buy_url":"https://felixchem.is/refer/642/","discount_code":"Bre10"}]}},{"name":"Melanotan 1","slug":"melanotan-1","url":"https://www.peptide-wiki.net/peptides/melanotan-1","aliases":["MT-1","Afamelanotide","CUV1647"],"category":{"id":"2e39ad27-8c66-43da-bb23-28301e76c31e","name":"Tanning","slug":"tanning"},"research_status":"prescription","research_status_label":"Prescription Only","administration_routes":["subcutaneous injection"],"half_life":"1-1.5 hours","summary":"A synthetic analog of alpha-MSH that stimulates melanin production for skin tanning. The more selective of the two Melanotan variants, with FDA-orphan drug status for erythropoietic protoporphyria.","mechanism":"Melanotan 1 selectively activates MC1R on melanocytes, stimulating melanin production without activating sexual arousal pathways.","benefits":["Promotes skin tanning without UV exposure","FDA-approved form for erythropoietic protoporphyria","Reduces UV-induced skin damage","More selective than Melanotan 2","Lower sexual arousal side effects"],"side_effects":["Nausea","Flushing","Fatigue","Mild libido changes","Injection site reactions","Possible new moles"],"dosage_info":{"unit":"mcg","notes":"Start with low doses to assess tolerance. Sunlight enhances tanning.","max_dose":1000,"min_dose":500,"frequency":"Loading: daily; Maintenance: 2-3x per week","weight_based":false},"cycle_length":"4-8 weeks loading, maintenance ongoing","stack_with":[{"slug":"melanotan-2","url":"https://www.peptide-wiki.net/peptides/melanotan-2"}],"molecular":{"formula":"C78H111N21O19","weight":null,"amino_acid_count":13,"cas_number":"75921-69-6","pubchem_cid":"71306","pubchem_url":"https://pubchem.ncbi.nlm.nih.gov/compound/71306"},"wada_banned":false,"wikipedia_url":"https://en.wikipedia.org/wiki/Afamelanotide","pricing":{"lowest_price_usd":29.99,"vendor_count":2,"in_stock_vendor_count":2,"vendors":[{"name":"FelixChem","price_usd":29.99,"quantity_mg":10,"form":"injectable","in_stock":true,"buy_url":"https://felixchem.is/refer/642/","discount_code":"Bre10"},{"name":"PeptideTech","price_usd":29.99,"quantity_mg":10,"form":"injectable","in_stock":true,"buy_url":"https://peptidetech.co/?ref=bre&utm_source=affiliate","discount_code":"BRE"}]}},{"name":"Melanotan 2","slug":"melanotan-2","url":"https://www.peptide-wiki.net/peptides/melanotan-2","aliases":["MT-2","Melanotan II"],"category":{"id":"2e39ad27-8c66-43da-bb23-28301e76c31e","name":"Tanning","slug":"tanning"},"research_status":"research_only","research_status_label":"Research Use Only","administration_routes":["subcutaneous injection","intranasal"],"half_life":"30-60 minutes","summary":"A broader-acting melanocortin peptide that stimulates both melanin production and the sexual arousal pathway. Produces potent tanning effects and is also used for erectile dysfunction.","mechanism":"Melanotan 2 activates multiple melanocortin receptors: MC1R for pigmentation, MC3R and MC4R for sexual arousal and appetite suppression.","benefits":["Strong melanin production and skin tanning","Libido enhancement","Appetite suppression","Erectile dysfunction support","Fat loss (modest)"],"side_effects":["Nausea (significant)","Spontaneous erections (males)","Facial flushing","Fatigue","Yawning","Potential kidney damage at high doses"],"dosage_info":{"unit":"mcg","notes":"Start with 250mcg to assess nausea tolerance. Higher doses not recommended.","max_dose":500,"min_dose":250,"frequency":"Daily loading, then 2-3x per week maintenance","weight_based":false},"cycle_length":"4-8 weeks loading","stack_with":[{"slug":"pt-141","url":"https://www.peptide-wiki.net/peptides/pt-141"}],"molecular":{"formula":"C50H69N15O9","weight":"1,024.2 Da","amino_acid_count":7,"cas_number":"121062-08-6","pubchem_cid":"92432","pubchem_url":"https://pubchem.ncbi.nlm.nih.gov/compound/92432"},"wada_banned":false,"wikipedia_url":"https://en.wikipedia.org/wiki/Melanotan_II","pricing":{"lowest_price_usd":29.99,"vendor_count":3,"in_stock_vendor_count":3,"vendors":[{"name":"FelixChem","price_usd":29.99,"quantity_mg":10,"form":"injectable","in_stock":true,"buy_url":"https://felixchem.is/refer/642/","discount_code":"Bre10"},{"name":"PeptideTech","price_usd":34.99,"quantity_mg":10,"form":"injectable","in_stock":true,"buy_url":"https://peptidetech.co/?ref=bre&utm_source=affiliate","discount_code":"BRE"},{"name":"Modern Aminos","price_usd":38,"quantity_mg":10,"form":"injectable","in_stock":true,"buy_url":"https://modernaminos.com/?ref=bre","discount_code":"BRE"}]}}]}