LL-37
Also known as: Cathelicidin Ā· hCAP18/LL-37 Ā· CAMP
The only human cathelicidin antimicrobial peptide, naturally produced by immune cells as a first-line defense. Has broad-spectrum antimicrobial, wound healing, and immunomodulatory properties.
What is LL-37? The only human cathelicidin antimicrobial peptide, naturally produced by immune cells as a first-line defense. Has broad-spectrum antimicrobial, wound healing, and immunomodulatory properties.
How does LL-37 work? LL-37 disrupts bacterial, fungal, and viral cell membranes through direct membrane permeabilization and acts as an immunomodulator by binding TLR receptors.
Benefits of LL-37: Broad-spectrum antimicrobial; Innate immune defense; Wound healing acceleration; Anti-inflammatory in chronic conditions; Potential anti-tumor properties
LL-37 dosage: Research compound. Topical formulations used for skin infections.
Research status: Research Only
Source: PeptideWiki ā https://www.peptide-wiki.net/peptides/ll-37
Mechanism of Action
LL-37 disrupts bacterial, fungal, and viral cell membranes through direct membrane permeabilization and acts as an immunomodulator by binding TLR receptors.
Benefits
- Broad-spectrum antimicrobial
- Innate immune defense
- Wound healing acceleration
- Anti-inflammatory in chronic conditions
- Potential anti-tumor properties
Side Effects & Risks
- Injection site irritation
- Limited long-term human data
- Paradoxically pro-inflammatory in some contexts
Where to Buy LL-37
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From
$49.99
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Storage & Reconstitution Guide
Storage Temperature
-20Ā°C (lyophilized)
24 months (lyophilized), 28 days (reconstituted)
Reconstitution Solvent
Bacteriostatic water (BAC water)
Swirl gently ā do not shake or vortex
Handling Notes
Protect lyophilized peptide from moisture and light. Once reconstituted, keep refrigerated. Discard if solution becomes cloudy or discolored. Use insulin syringe for precise dosing.
Step-by-Step Reconstitution
Gather supplies
BAC water, insulin syringe, alcohol swabs, vial
Disinfect tops
Swab rubber stoppers of both vials with alcohol
Draw BAC water
Pull desired mL of BAC water into syringe
Inject slowly
Inject BAC water down the side of the peptide vial, swirl gently to dissolve
Research Protocol
- Dose Range
- 100ā500 mcg
- Frequency
- Daily to 3x weekly
- Cycle
- 4-8 weeks
- Routes
- subcutaneous injectiontopical
- Notes
- Research compound. Topical formulations used for skin infections.
Legal & Regulatory Status
Sold for research purposes only. Not for human use. Laws vary by country.
Commonly Stacked With
View all peptide stacks āExternal Resources
PeptideWiki Research Team
Evidence-based research data sourced from PubMed and ClinicalTrials.gov Ā· Last updated: February 25, 2026
Frequently Asked Questions About LL-37
What is LL-37?ā¾
The only human cathelicidin antimicrobial peptide, naturally produced by immune cells as a first-line defense. Has broad-spectrum antimicrobial, wound healing, and immunomodulatory properties.
What are the benefits of LL-37?ā¾
Broad-spectrum antimicrobial
What are the benefits of LL-37?ā¾
Innate immune defense
What are the side effects of LL-37?ā¾
Injection site irritation
What is the recommended dosage for LL-37?ā¾
Research compound. Topical formulations used for skin infections.
How long should a LL-37 cycle last?ā¾
4-8 weeks
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