PeptideWiki

Peptide Stacks

Curated peptide combinations for specific goals, with protocols and rationale.

Stack #1

Classic GH Stack

Muscle growth, fat loss, body recomposition

The most popular peptide stack for muscle growth and body recomposition. CJC-1295 provides sustained GHRH stimulation while Ipamorelin adds selective GH pulses without cortisol elevation.

Protocol

CJC-1295: 300mcg 3x weekly + Ipamorelin: 200–300mcg daily before bed. Run for 8–12 weeks.

Stack #2

Ultimate Healing Stack

Injury recovery, tissue repair, anti-inflammation

BPC-157 and TB-500 are highly complementary — BPC-157 works locally for tissue repair while TB-500 works systemically. Together they cover both acute and chronic injury healing.

Protocol

BPC-157: 250–500mcg twice daily near injury site + TB-500: 5mg 2x per week. Run for 4–6 weeks.

Stack #3

Anti-Aging Protocol

Anti-aging, longevity, immune optimization

A comprehensive anti-aging stack combining telomere support (Epithalon), skin/tissue regeneration (GHK-Cu), and immune optimization (Thymosin Alpha-1).

Protocol

Epithalon: 5–10mg daily for 10–20 days (2x/year). GHK-Cu: Topical daily + 1–3mg injectable 2x/week ongoing. Thymosin Alpha-1: 1.6mg 2x/week for 6 weeks.

Stack #4

Cognitive Enhancement Stack

Cognitive enhancement, anxiety reduction, focus

Semax and Selank complement each other perfectly — Semax provides stimulating cognitive enhancement and BDNF upregulation while Selank provides anxiolytic balance and emotional stability.

Protocol

Semax: 300–600mcg nasal spray in the morning. Selank: 250–500mcg nasal spray in the afternoon or as needed for anxiety. 2–4 week cycles.

Stack #5

Weight Loss Stack

Fat loss, appetite suppression, metabolic optimization

Semaglutide provides powerful appetite suppression and metabolic benefits while AOD-9604 directly targets fat metabolism through GH fragment activity — complementary mechanisms.

Protocol

Semaglutide: Start 0.25mg weekly, titrate up. AOD-9604: 250–500mcg daily on empty stomach. Monitor blood glucose.

Stack #6

Muscle Building Power Stack

Maximum muscle growth and strength

Combines upstream GH stimulation (CJC-1295 + Ipamorelin) with direct muscle-building action (IGF-1 LR3) for maximum anabolic effect. Advanced stack — not for beginners.

Protocol

CJC-1295 + Ipamorelin as foundation. Add IGF-1 LR3: 40–80mcg post-workout. Always take with carbohydrates. 4–6 week cycles with breaks.

Stack #7

Longevity Protocol

Longevity, anti-aging, cellular health

A comprehensive longevity stack targeting telomere extension (Epithalon), mitochondrial health (SS-31 or MOTS-C), senescent cell clearance (FOXO4-DRI), and NAD+ restoration (NMN).

Protocol

Epithalon: 5–10mg daily for 10–20 days, 2x/year. SS-31: 4–10mg/day SubQ for 4–8 weeks. NMN: 500mg/day oral ongoing. GHK-Cu: topical daily + injectable 2x/week ongoing.

Stack #8

Gut Healing Protocol

Gut healing, leaky gut, IBD, intestinal repair

The most effective combination for intestinal healing, leaky gut, IBD, and GI inflammation. BPC-157 heals tissue, KPV provides anti-inflammatory action, and Larazotide seals tight junctions.

Protocol

BPC-157: 250–500mcg oral twice daily on empty stomach. KPV: 250–500mcg oral twice daily. Larazotide: 500mcg–1mg oral 3x daily before meals. Run 4–8 weeks.

Stack #9

Senolytic Protocol

Senescent cell clearance, anti-aging, immune rebuild

FOXO4-DRI selectively destroys senescent cells while Epithalon protects telomere length and thymosin alpha-1 rebuilds immune function following senescent cell clearance.

Protocol

FOXO4-DRI: 5–10mg SubQ for 3 consecutive days per monthly cycle. Epithalon: 5mg/day for 10–20 days, 2x/year. Thymosin Alpha-1: 1.6mg 2x/week for 6 weeks following FOXO4-DRI cycle.

Stack #10

Exercise Mimetic Stack

Metabolic enhancement, endurance, insulin sensitivity

AICAR activates AMPK and MOTS-C activates skeletal muscle metabolism independently — together they activate complementary metabolic pathways that mimic the effects of endurance exercise.

Protocol

AICAR: 500mg SubQ daily for 2–4 weeks. MOTS-C: 5–10mg 3–5x/week. SLU-PP-332: 1mg oral daily. Cycle 4–8 weeks.

Important: All stacks listed are for research purposes only. Combination protocols should be thoroughly researched. These represent commonly discussed protocols in the research community and do not constitute medical advice.