GHK-Cu
Also known as: GHK-Copper · Copper Peptide · Copper Tripeptide-1
A naturally occurring copper-binding tripeptide that declines with age. Promotes skin rejuvenation, wound healing, hair growth, and anti-inflammatory effects. One of the most studied anti-aging peptides.
Mechanism of Action
GHK-Cu activates copper-dependent enzymes for collagen and elastin synthesis, promotes wound healing via VEGF and FGF, activates stem cells in hair follicles, and resets aging-related gene expression patterns.
Amino Acid Sequence (3 AAs)
Gly-His-Lys · Cu²⁺
Benefits
- Stimulates collagen and elastin production
- Reduces fine lines and wrinkles
- Accelerates wound healing
- Promotes hair growth
- Anti-inflammatory and antioxidant
- Potential anti-cancer properties
- Skin tightening and rejuvenation
Side Effects & Risks
- Topical: mild skin irritation initially
- Injectable: injection site reactions
- Very well tolerated overall
Where to Buy GHK-Cu
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From
$29.99
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Storage & Reconstitution Guide
Storage Temperature
4°C (solution), -20°C (lyophilized)
24 months (lyophilized), 28 days (reconstituted)
Reconstitution Solvent
Sterile water or saline for injectable; cosmetic base for topical
Swirl gently — do not shake or vortex
Handling Notes
Protect lyophilized peptide from moisture and light. Once reconstituted, keep refrigerated. Discard if solution becomes cloudy or discolored. Use insulin syringe for precise dosing.
Step-by-Step Reconstitution
Gather supplies
BAC water, insulin syringe, alcohol swabs, vial
Disinfect tops
Swab rubber stoppers of both vials with alcohol
Draw BAC water
Pull desired mL of BAC water into syringe
Inject slowly
Inject BAC water down the side of the peptide vial, swirl gently to dissolve
Preclinical Research & Reviews1
GHK-Cu May Prevent Oxidative Stress in Skin by Regulating Copper
GHK-Cu modulates over 4,000 human genes and provides significant antioxidant protection.
Molecular Structure
- CAS Number
- 49557-75-7
- PubChem CID
- 342538
- Molecular Weight
- 403.92 Da (Cu complex)
- Mol. Formula
- C14H24CuN6O4
- Amino Acids
- 3-AA peptide
- IUPAC Name
- 6-amino-2-[[2-[(2-aminoacetyl)amino]-3-(1H-imidazol-5-yl)propanoyl]amino]hexanoic acid; copper(2+)
- Wikipedia
- View article
Research Protocol
- Dose Range
- 1–3 mg
- Frequency
- Daily topical or 1-3x per week injectable
- Cycle
- Ongoing
- Routes
- topicalsubcutaneous injection
- Notes
- Available in topical creams/serums and injectable form.
Legal & Regulatory Status
Sold for research purposes only. Not for human use. Laws vary by country.
Commonly Stacked With
View all peptide stacks →External Resources
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