PeptideWiki
Research OnlyActin-Binding Peptide WADA Banned๐Ÿฉน Healing & Recovery

TB-500

Also known as: Thymosin Beta-4 ยท Thymosin Beta4 ยท TB500 ยท LKKTETQ

A synthetic version of Thymosin Beta-4, a naturally occurring protein present in nearly all human cells. Promotes cellular healing, anti-inflammation, and tissue regeneration throughout the entire body.

43 AAs
MW: 4,963.4 Da
CAS: 77591-33-4

From

$34.99

6 vendor options

Shop with Discount

Mechanism of Action

TB-500 upregulates actin, promoting cell migration, proliferation, and differentiation. It stimulates angiogenesis, reduces inflammation through cytokine modulation, and exhibits systemic healing properties.

Amino Acid Sequence (43 AAs)

Ac-SDKPDMAEIEKFDKSKLKKTETQEKNPLPSKETIEQEKQAGES

Benefits

  • Systemic healing and tissue repair
  • Accelerated recovery from injury
  • Anti-inflammatory effects
  • Improved flexibility and joint mobility
  • Hair growth stimulation
  • Neurological recovery
  • Cardiovascular tissue repair
  • Enhanced endurance

Side Effects & Risks

  • Mild headaches
  • Lethargy immediately after injection
  • Nausea
  • Injection site pain

Where to Buy TB-500

6 options across 5 vendors ยท Sorted cheapest first ยท All include direct product link

From

$34.99

Best Price$34.99/ 5mg
$7.00/mg
PeptideTechBest Value COAOut of Stock
injectable5mg vial direct product link
10% off code:BRE
$39.99/ 5mg
$8.00/mg
Vandl LabsWidest Selection COA
injectable5mg vial direct product link
10% off code:BRE
$48.00/ 10mg
$4.80/mg
Modern AminosBudget-Friendly COA
injectable10mg vial direct product link
10% off code:BRE
$54.99/ 10mg
$5.50/mg
PeptideTechBest Value COAOut of Stock
injectable10mg vial direct product link
10% off code:BRE
$69.99/ 10mg
$7.00/mg
FelixChemTop Rated COA
injectable10mg vial
10% off code:Bre10
$79.99/ 30mg
$2.67/mg
Modified AminosUS-Made COA
oral30mg vial direct product link
10% off code:BRE

All links are affiliate links โ€” PeptideWiki earns a commission at no extra cost to you. Coupon codes apply at checkout. Prices and availability may change. Always verify COA before purchasing.

Storage & Reconstitution Guide

Storage Temperature

-20ยฐC lyophilized, 4ยฐC reconstituted

24 months (lyophilized), 28 days (reconstituted)

Reconstitution Solvent

Bacteriostatic water (BAC water)

Swirl gently โ€” do not shake or vortex

Handling Notes

Protect lyophilized peptide from moisture and light. Once reconstituted, keep refrigerated. Discard if solution becomes cloudy or discolored. Use insulin syringe for precise dosing.

Step-by-Step Reconstitution

1

Gather supplies

BAC water, insulin syringe, alcohol swabs, vial

2

Disinfect tops

Swab rubber stoppers of both vials with alcohol

3

Draw BAC water

Pull desired mL of BAC water into syringe

4

Inject slowly

Inject BAC water down the side of the peptide vial, swirl gently to dissolve

Preclinical Research & Reviews1

๐Ÿ€ Animal Study

Thymosin beta4 promotes corneal wound healing

Sosne G, et al.ยทExperimental Eye Researchยท2001

Thymosin beta-4 significantly accelerated corneal wound healing through actin regulation.

Molecular Structure

Molecular structure of TB-500
CAS Number
77591-33-4
PubChem CID
16132341
Molecular Weight
4,963.4 Da
Mol. Formula
C212H350N56O78S
Amino Acids
43-AA peptide
Wikipedia
View article

Research Protocol

Dose Range
5โ€“20 mg
Frequency
2x per week loading, then 1x per week maintenance
Cycle
4-6 weeks (loading)
Routes
subcutaneous injectionintramuscular injection
Notes
Stack with BPC-157 for synergistic healing.
Open Dosage Calculator โ†’

Legal & Regulatory Status

Research StatusResearch Only
WADA Status Prohibited
FDA ClassificationNot Approved
Originsynthetic

Sold for research purposes only. Not for human use. Laws vary by country.

Commonly Stacked With

View all peptide stacks โ†’

External Resources

More in Healing & Recovery

Cardiogen

Heart peptide bioregulator

A tetrapeptide cardiac bioregulator from the Khavinson series targeting myocardial tissue. Normalizes myocardial cell function, reduces cardiac oxidative stress, and provides cardioprotection against ischemia and aging-related cardiac decline. Studied for heart failure, cardiomyopathy, and post-infarction recovery.

Research Only๐Ÿ’‰ SubQ
Cartalax

Cartilage peptide bioregulator

A cartilage and bone-targeting peptide bioregulator from the Khavinson series. Studied for arthritis, osteochondrosis, fracture recovery, and joint aging. Stimulates chondrocyte proliferation and collagen synthesis in cartilage tissue, supporting structural repair and maintenance of joint integrity.

Research Only๐Ÿ’‰ SubQ
ARA-290

Cibinetide

A synthetic 11-amino acid peptide that mimics the tissue-protective actions of erythropoietin without its erythropoietic effects. Highly effective for neuropathic pain and nerve repair.

Clinical Trials๐Ÿ’‰ SubQ
Svetinorm

BioLiver

A liver-targeting tetrapeptide bioregulator. Normalizes hepatocyte function, reduces liver fibrosis, improves bile acid metabolism, and protects against hepatotoxicity. Studied for NAFLD, alcohol-related liver damage, hepatitis recovery, and liver aging.

Research Only๐Ÿ’‰ SubQ