Selank
Also known as: N-Acetyl Selank · Tuftsin Analog · TP-7
A synthetic heptapeptide derived from tuftsin that exhibits anxiolytic, nootropic, and immunomodulatory effects. Considered a milder anxiolytic counterpart to Semax with a strong safety profile.
What is Selank? A synthetic heptapeptide derived from tuftsin that exhibits anxiolytic, nootropic, and immunomodulatory effects. Considered a milder anxiolytic counterpart to Semax with a strong safety profile.
How does Selank work? Selank modulates GABA-A receptors, serotonin, and enkephalin systems. It also regulates BDNF expression and is immunomodulatory via IL-6 and interferon modulation.
Benefits of Selank: Potent anxiolytic without sedation or dependence; Improves mood and emotional stability; Cognitive enhancement; Immunomodulatory properties; Neuroprotective; Reduces stress response
Selank dosage: Can be stacked with Semax for complementary effects.
Selank half-life: Minutes
Research status: Prescription
Source: PeptideWiki — https://www.peptide-wiki.net/peptides/selank
Mechanism of Action
Selank modulates GABA-A receptors, serotonin, and enkephalin systems. It also regulates BDNF expression and is immunomodulatory via IL-6 and interferon modulation.
Amino Acid Sequence (7 AAs)
Thr-Lys-Pro-Arg-Pro-Gly-Pro
Benefits
- Potent anxiolytic without sedation or dependence
- Improves mood and emotional stability
- Cognitive enhancement
- Immunomodulatory properties
- Neuroprotective
- Reduces stress response
Side Effects & Risks
- Mild nasal irritation
- Mild headaches
- Slight fatigue initially
- Generally very well tolerated
Where to Buy Selank
3 options across 3 vendors · Sorted cheapest first · All include direct product link
From
$34.99
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Storage & Reconstitution Guide
Storage Temperature
-20°C lyophilized, 4°C reconstituted
24 months (lyophilized), 28 days (reconstituted)
Reconstitution Solvent
Saline (0.9% NaCl) for nasal spray
Swirl gently — do not shake or vortex
Handling Notes
Protect lyophilized peptide from moisture and light. Once reconstituted, keep refrigerated. Discard if solution becomes cloudy or discolored. Use insulin syringe for precise dosing.
Step-by-Step Reconstitution
Gather supplies
BAC water, insulin syringe, alcohol swabs, vial
Disinfect tops
Swab rubber stoppers of both vials with alcohol
Draw BAC water
Pull desired mL of BAC water into syringe
Inject slowly
Inject BAC water down the side of the peptide vial, swirl gently to dissolve
Preclinical Research & Reviews1
Selank has anxiolytic properties and modulates the serotoninergic system
Selank demonstrates anxiolytic effects through serotonergic and GABAergic modulation.
Molecular Structure
- CAS Number
- 129954-34-3
- PubChem CID
- 155489759
- Molecular Weight
- 751.9 Da
- Mol. Formula
- C33H57N11O10
- Amino Acids
- 7-AA peptide
- Wikipedia
- View article
Research Protocol
- Dose Range
- 250–500 mcg
- Frequency
- Once or twice daily via nasal spray
- Cycle
- 2-4 weeks
- Half-Life
- Minutes
- Routes
- intranasal
- Notes
- Can be stacked with Semax for complementary effects.
Legal & Regulatory Status
Sold for research purposes only. Not for human use. Laws vary by country.
Commonly Stacked With
View all peptide stacks →External Resources
PeptideWiki Research Team
Evidence-based research data sourced from PubMed and ClinicalTrials.gov · Last updated: February 25, 2026
Frequently Asked Questions About Selank
What is Selank?▾
A synthetic heptapeptide derived from tuftsin that exhibits anxiolytic, nootropic, and immunomodulatory effects. Considered a milder anxiolytic counterpart to Semax with a strong safety profile.
What are the benefits of Selank?▾
Potent anxiolytic without sedation or dependence
What are the benefits of Selank?▾
Improves mood and emotional stability
What are the side effects of Selank?▾
Mild nasal irritation
What is the recommended dosage for Selank?▾
Can be stacked with Semax for complementary effects.
How long should a Selank cycle last?▾
2-4 weeks
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