MOTS-C
Also known as: Mitochondrial Open Reading Frame of the 12S rRNA-c
A mitochondria-derived peptide that acts as a metabolic regulator, improving insulin sensitivity, exercise capacity, and potentially mimicking caloric restriction.
Mechanism of Action
MOTS-C is a 16-amino acid peptide produced by mitochondria that activates the AMPK pathway in skeletal muscle, improving glucose uptake and fatty acid oxidation.
Amino Acid Sequence (16 AAs)
MRWQEMGYIFFYKLKR
Benefits
- Improves insulin sensitivity
- Increases metabolic flexibility
- Enhances exercise performance and endurance
- Anti-aging and longevity potential
- Reduces metabolic syndrome markers
Side Effects & Risks
- Limited human data
- Injection site reactions
Where to Buy MOTS-C
3 options across 3 vendors · Sorted cheapest first · All include direct product link
From
$44.99
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Storage & Reconstitution Guide
Storage Temperature
-20°C lyophilized, 4°C reconstituted
24 months (lyophilized), 28 days (reconstituted)
Reconstitution Solvent
Bacteriostatic water (BAC water)
Swirl gently — do not shake or vortex
Handling Notes
Protect lyophilized peptide from moisture and light. Once reconstituted, keep refrigerated. Discard if solution becomes cloudy or discolored. Use insulin syringe for precise dosing.
Step-by-Step Reconstitution
Gather supplies
BAC water, insulin syringe, alcohol swabs, vial
Disinfect tops
Swab rubber stoppers of both vials with alcohol
Draw BAC water
Pull desired mL of BAC water into syringe
Inject slowly
Inject BAC water down the side of the peptide vial, swirl gently to dissolve
Research Protocol
- Dose Range
- 5–10 mg
- Frequency
- 3-5x per week, subcutaneous or intramuscular
- Cycle
- 8-12 weeks
- Routes
- subcutaneous injectionintramuscular injection
- Notes
- Research peptide with promising but limited human data.
Legal & Regulatory Status
Sold for research purposes only. Not for human use. Laws vary by country.
Commonly Stacked With
View all peptide stacks →External Resources
Chemical Properties
- CAS Number
- 1627580-64-6
- Mol. Weight
- 2,174.62 Da
- Formula
- C92H152N28O30S
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