5-Amino-1MQ
Also known as: 5-Amino-1-methylquinolinium · 5A1MQ
A small molecule inhibitor of NNMT enzyme that boosts metabolism and promotes fat cell apoptosis. Shows promise as a novel anti-obesity agent in preclinical research.
What is 5-Amino-1MQ? A small molecule inhibitor of NNMT enzyme that boosts metabolism and promotes fat cell apoptosis. Shows promise as a novel anti-obesity agent in preclinical research.
How does 5-Amino-1MQ work? NNMT is an enzyme that suppresses the metabolic rate. 5-Amino-1MQ blocks NNMT, increases the NAD+/NADH ratio, activates SIRT1, and upregulates metabolic pathways leading to fat reduction.
Benefits of 5-Amino-1MQ: Inhibits NNMT to boost resting metabolic rate; Promotes fat cell shrinkage and apoptosis; Increases NAD+ levels; Potential for muscle sparing during weight loss
5-Amino-1MQ dosage: Research compound with limited human clinical data.
Research status: Research Only
Source: PeptideWiki — https://www.peptide-wiki.net/peptides/5-amino-1mq
Mechanism of Action
NNMT is an enzyme that suppresses the metabolic rate. 5-Amino-1MQ blocks NNMT, increases the NAD+/NADH ratio, activates SIRT1, and upregulates metabolic pathways leading to fat reduction.
Benefits
- Inhibits NNMT to boost resting metabolic rate
- Promotes fat cell shrinkage and apoptosis
- Increases NAD+ levels
- Potential for muscle sparing during weight loss
Side Effects & Risks
- Limited human data available
- Potential GI discomfort
Where to Buy 5-Amino-1MQ
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From
$58.00
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Storage & Reconstitution Guide
Storage Temperature
-20°C (lyophilized)
24 months (lyophilized), 28 days (reconstituted)
Reconstitution Solvent
Bacteriostatic water (BAC water)
Swirl gently — do not shake or vortex
Handling Notes
Protect lyophilized peptide from moisture and light. Once reconstituted, keep refrigerated. Discard if solution becomes cloudy or discolored. Use insulin syringe for precise dosing.
Step-by-Step Reconstitution
Gather supplies
BAC water, insulin syringe, alcohol swabs, vial
Disinfect tops
Swab rubber stoppers of both vials with alcohol
Draw BAC water
Pull desired mL of BAC water into syringe
Inject slowly
Inject BAC water down the side of the peptide vial, swirl gently to dissolve
Research Protocol
- Dose Range
- 50–100 mg
- Frequency
- Once or twice daily oral
- Cycle
- 4-8 weeks
- Routes
- oral
- Notes
- Research compound with limited human clinical data.
Legal & Regulatory Status
Sold for research purposes only. Not for human use. Laws vary by country.
Commonly Stacked With
View all peptide stacks →External Resources
PeptideWiki Research Team
Evidence-based research data sourced from PubMed and ClinicalTrials.gov · Last updated: February 25, 2026
Frequently Asked Questions About 5-Amino-1MQ
What is 5-Amino-1MQ?▾
A small molecule inhibitor of NNMT enzyme that boosts metabolism and promotes fat cell apoptosis. Shows promise as a novel anti-obesity agent in preclinical research.
What are the benefits of 5-Amino-1MQ?▾
Inhibits NNMT to boost resting metabolic rate
What are the benefits of 5-Amino-1MQ?▾
Promotes fat cell shrinkage and apoptosis
What are the side effects of 5-Amino-1MQ?▾
Limited human data available
What is the recommended dosage for 5-Amino-1MQ?▾
Research compound with limited human clinical data.
How long should a 5-Amino-1MQ cycle last?▾
4-8 weeks
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