Macimorelin
Also known as: AEZS-130 · Macrilen
An orally active ghrelin receptor agonist FDA-approved as a diagnostic test for adult growth hormone deficiency. Provides a convenient oral GH stimulation test.
Mechanism of Action
Macimorelin activates ghrelin receptors (GHS-R1a) in the pituitary, stimulating GH release. FDA-approved specifically for diagnosing GH deficiency in adults.
Benefits
- FDA-approved diagnostic for adult GH deficiency
- Oral administration for testing
- Reliable GH stimulation
- Investigated for therapeutic GH deficiency treatment
Side Effects & Risks
- Nausea
- Headache
- Dysgeusia (taste disturbance)
- Dizziness
- Fatigue
Where to Buy Macimorelin
1 option across 1 vendor · Sorted cheapest first · All include direct product link
From
$89.99
All links are affiliate links — PeptideWiki earns a commission at no extra cost to you. Coupon codes apply at checkout. Prices and availability may change. Always verify COA before purchasing.
Storage & Reconstitution Guide
Storage Temperature
-20°C (lyophilized)
24 months (lyophilized), 28 days (reconstituted)
Reconstitution Solvent
Bacteriostatic water (BAC water)
Swirl gently — do not shake or vortex
Handling Notes
Protect lyophilized peptide from moisture and light. Once reconstituted, keep refrigerated. Discard if solution becomes cloudy or discolored. Use insulin syringe for precise dosing.
Step-by-Step Reconstitution
Gather supplies
BAC water, insulin syringe, alcohol swabs, vial
Disinfect tops
Swab rubber stoppers of both vials with alcohol
Draw BAC water
Pull desired mL of BAC water into syringe
Inject slowly
Inject BAC water down the side of the peptide vial, swirl gently to dissolve
Research Protocol
- Dose Range
- 0.5 mg/kg/kg
- Frequency
- Single dose (diagnostic use)
- Cycle
- Single dose (diagnostic)
- Half-Life
- 4 hours
- Routes
- oral
- Notes
- Diagnostic dose: 0.5mg/kg oral, single administration.
Legal & Regulatory Status
Sold for research purposes only. Not for human use. Laws vary by country.
External Resources
More in Experimental
FTPP
A highly experimental proapoptotic peptide that selectively destroys the blood supply to white adipose tissue. Dramatic fat loss in animal models but significant renal toxicity concerns.
PNC27
A chimeric anticancer peptide fusing a p53 MDM-2 binding domain with a penetratin membrane-translocation region. Selectively forms pores in cancer cell membranes that overexpress HDM-2 (human MDM-2 oncoprotein), causing rapid membranolysis and cancer cell death while sparing normal cells.