Macimorelin
Also known as: AEZS-130 · Macrilen
An orally active ghrelin receptor agonist FDA-approved as a diagnostic test for adult growth hormone deficiency. Provides a convenient oral GH stimulation test.
What is Macimorelin? An orally active ghrelin receptor agonist FDA-approved as a diagnostic test for adult growth hormone deficiency. Provides a convenient oral GH stimulation test.
How does Macimorelin work? Macimorelin activates ghrelin receptors (GHS-R1a) in the pituitary, stimulating GH release. FDA-approved specifically for diagnosing GH deficiency in adults.
Benefits of Macimorelin: FDA-approved diagnostic for adult GH deficiency; Oral administration for testing; Reliable GH stimulation; Investigated for therapeutic GH deficiency treatment
Macimorelin dosage: Diagnostic dose: 0.5mg/kg oral, single administration.
Macimorelin half-life: 4 hours
Research status: FDA Approved
Source: PeptideWiki — https://www.peptide-wiki.net/peptides/macimorelin
Mechanism of Action
Macimorelin activates ghrelin receptors (GHS-R1a) in the pituitary, stimulating GH release. FDA-approved specifically for diagnosing GH deficiency in adults.
Benefits
- FDA-approved diagnostic for adult GH deficiency
- Oral administration for testing
- Reliable GH stimulation
- Investigated for therapeutic GH deficiency treatment
Side Effects & Risks
- Nausea
- Headache
- Dysgeusia (taste disturbance)
- Dizziness
- Fatigue
Where to Buy Macimorelin
1 option across 1 vendor · Sorted cheapest first · All include direct product link
From
$89.99
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Storage & Reconstitution Guide
Storage Temperature
-20°C (lyophilized)
24 months (lyophilized), 28 days (reconstituted)
Reconstitution Solvent
Bacteriostatic water (BAC water)
Swirl gently — do not shake or vortex
Handling Notes
Protect lyophilized peptide from moisture and light. Once reconstituted, keep refrigerated. Discard if solution becomes cloudy or discolored. Use insulin syringe for precise dosing.
Step-by-Step Reconstitution
Gather supplies
BAC water, insulin syringe, alcohol swabs, vial
Disinfect tops
Swab rubber stoppers of both vials with alcohol
Draw BAC water
Pull desired mL of BAC water into syringe
Inject slowly
Inject BAC water down the side of the peptide vial, swirl gently to dissolve
Research Protocol
- Dose Range
- 0.5 mg/kg/kg
- Frequency
- Single dose (diagnostic use)
- Cycle
- Single dose (diagnostic)
- Half-Life
- 4 hours
- Routes
- oral
- Notes
- Diagnostic dose: 0.5mg/kg oral, single administration.
Legal & Regulatory Status
Sold for research purposes only. Not for human use. Laws vary by country.
External Resources
PeptideWiki Research Team
Evidence-based research data sourced from PubMed and ClinicalTrials.gov · Last updated: February 25, 2026
Frequently Asked Questions About Macimorelin
What is Macimorelin?▾
An orally active ghrelin receptor agonist FDA-approved as a diagnostic test for adult growth hormone deficiency. Provides a convenient oral GH stimulation test.
What are the benefits of Macimorelin?▾
FDA-approved diagnostic for adult GH deficiency
What are the benefits of Macimorelin?▾
Oral administration for testing
What are the side effects of Macimorelin?▾
Nausea
What is the recommended dosage for Macimorelin?▾
Diagnostic dose: 0.5mg/kg oral, single administration.
How long should a Macimorelin cycle last?▾
Single dose (diagnostic)
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