GHRP-6
Also known as: Growth Hormone Releasing Peptide-6 · GHRP6
One of the first synthetic GHRPs developed, GHRP-6 is a potent GH secretagogue that also significantly stimulates appetite through ghrelin receptor activation.
What is GHRP-6? One of the first synthetic GHRPs developed, GHRP-6 is a potent GH secretagogue that also significantly stimulates appetite through ghrelin receptor activation.
How does GHRP-6 work? GHRP-6 is a hexapeptide that acts on GHS-R receptors to stimulate GH release from the anterior pituitary. It also acts as a functional analog of ghrelin, significantly increasing appetite.
Benefits of GHRP-6: Potent GH release; Significant increase in lean muscle mass; Enhanced recovery and tissue repair; Increased appetite (beneficial for hard gainers); IGF-1 elevation; Anti-inflammatory properties
GHRP-6 dosage: Stack with CJC-1295 for synergistic GH release.
GHRP-6 half-life: 15-60 minutes
Research status: Research Only
Source: PeptideWiki — https://www.peptide-wiki.net/peptides/ghrp-6
Mechanism of Action
GHRP-6 is a hexapeptide that acts on GHS-R receptors to stimulate GH release from the anterior pituitary. It also acts as a functional analog of ghrelin, significantly increasing appetite.
Amino Acid Sequence (6 AAs)
His-D-Trp-Ala-Trp-D-Phe-Lys-NH₂
Benefits
- Potent GH release
- Significant increase in lean muscle mass
- Enhanced recovery and tissue repair
- Increased appetite (beneficial for hard gainers)
- IGF-1 elevation
- Anti-inflammatory properties
Side Effects & Risks
- Strong hunger/appetite increase
- Elevated cortisol and prolactin
- Water retention
- Lethargy
- Potential desensitization
Where to Buy GHRP-6
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$29.99
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Storage & Reconstitution Guide
Storage Temperature
-20°C lyophilized, 4°C reconstituted
24 months (lyophilized), 28 days (reconstituted)
Reconstitution Solvent
Bacteriostatic water (BAC water)
Swirl gently — do not shake or vortex
Handling Notes
Protect lyophilized peptide from moisture and light. Once reconstituted, keep refrigerated. Discard if solution becomes cloudy or discolored. Use insulin syringe for precise dosing.
Step-by-Step Reconstitution
Gather supplies
BAC water, insulin syringe, alcohol swabs, vial
Disinfect tops
Swab rubber stoppers of both vials with alcohol
Draw BAC water
Pull desired mL of BAC water into syringe
Inject slowly
Inject BAC water down the side of the peptide vial, swirl gently to dissolve
Molecular Structure
- CAS Number
- 87616-84-0
- PubChem CID
- 72941687
- Molecular Weight
- 872.44 Da
- Mol. Formula
- C46H56N12O6
- Amino Acids
- 6-AA peptide
- Wikipedia
- View article
Research Protocol
- Dose Range
- 100–300 mcg
- Frequency
- 1-3x daily, 30-45 min before meals
- Cycle
- 8-12 weeks
- Half-Life
- 15-60 minutes
- Routes
- subcutaneous injectionintranasal
- Notes
- Stack with CJC-1295 for synergistic GH release.
Legal & Regulatory Status
Sold for research purposes only. Not for human use. Laws vary by country.
Commonly Stacked With
View all peptide stacks →External Resources
PeptideWiki Research Team
Evidence-based research data sourced from PubMed and ClinicalTrials.gov · Last updated: February 25, 2026
Frequently Asked Questions About GHRP-6
What is GHRP-6?▾
One of the first synthetic GHRPs developed, GHRP-6 is a potent GH secretagogue that also significantly stimulates appetite through ghrelin receptor activation.
What are the benefits of GHRP-6?▾
Potent GH release
What are the benefits of GHRP-6?▾
Significant increase in lean muscle mass
What are the side effects of GHRP-6?▾
Strong hunger/appetite increase
What is the recommended dosage for GHRP-6?▾
Stack with CJC-1295 for synergistic GH release.
How long should a GHRP-6 cycle last?▾
8-12 weeks
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