CJC-1295 No DAC (Mod GRF 1-29)
Also known as: Modified GRF 1-29 · CJC-1295 no DAC · Mod GRF · Sermorelin-like · GRF(1-29)
A synthetic 29-amino acid GHRH analog with 4 amino acid substitutions that improve stability and receptor affinity compared to Sermorelin. Unlike CJC-1295 DAC, it has no Drug Affinity Complex, giving it a short 30-minute half-life that mimics the body's natural pulsatile GHRH secretion when co-administered with a GHRP.
Mechanism of Action
Mod GRF 1-29 binds to GHRH receptors on pituitary somatotrophs and stimulates GH release in synchrony with an administered GHRP. Because of its short half-life, it produces a sharp, physiological GH pulse rather than the sustained elevation from CJC-1295 DAC. The 4 amino acid substitutions make it more stable than Sermorelin.
Benefits
- Produces physiological pulsatile GH release
- More stable than Sermorelin
- Synergistic with any GHRP for 3-5x GH amplification
- Flexible dosing schedule
- Lower desensitization risk vs. DAC version
- More affordable than DAC version
Side Effects & Risks
- Very short half-life requires co-administration with GHRP
- Must be dosed 1-3x daily (more injections)
- Water retention
- Mild headache
Where to Buy CJC-1295 No DAC (Mod GRF 1-29)
1 option across 1 vendor · Sorted cheapest first · All include direct product link
From
$39.95
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Storage & Reconstitution Guide
Storage Temperature
-20°C (lyophilized)
24 months (lyophilized), 28 days (reconstituted)
Reconstitution Solvent
Bacteriostatic water (BAC water)
Swirl gently — do not shake or vortex
Handling Notes
Protect lyophilized peptide from moisture and light. Once reconstituted, keep refrigerated. Discard if solution becomes cloudy or discolored. Use insulin syringe for precise dosing.
Step-by-Step Reconstitution
Gather supplies
BAC water, insulin syringe, alcohol swabs, vial
Disinfect tops
Swab rubber stoppers of both vials with alcohol
Draw BAC water
Pull desired mL of BAC water into syringe
Inject slowly
Inject BAC water down the side of the peptide vial, swirl gently to dissolve
Molecular Structure
- CAS Number
- 863288-34-0
- PubChem CID
- 863288
- Molecular Weight
- 3,367 Da
- Mol. Formula
- C152H252N44O42
- Amino Acids
- 29-AA peptide
Research Protocol
- Dose Range
- 100–200 mcg
- Frequency
- 1-3x daily, always with a GHRP
- Cycle
- 8-16 weeks
- Half-Life
- 30 minutes
- Routes
- subcutaneous injection
- Notes
- MUST be co-administered with a GHRP (Ipamorelin, GHRP-6, etc.) within 30 seconds for synergistic effect. Dose: 100-200mcg per injection.
Legal & Regulatory Status
Sold for research purposes only. Not for human use. Laws vary by country.
Commonly Stacked With
View all peptide stacks →External Resources
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