Hexarelin
Also known as: Examorelin · EP 23905
A synthetic hexapeptide GHRP with the highest GH-releasing potency among the GHRP family. Notable for both its muscle-building effects and documented cardiovascular benefits.
What is Hexarelin? A synthetic hexapeptide GHRP with the highest GH-releasing potency among the GHRP family. Notable for both its muscle-building effects and documented cardiovascular benefits.
How does Hexarelin work? Hexarelin is a 6-amino acid synthetic peptide that binds both the GHS-R receptor and the CD36 scavenger receptor. It stimulates strong GH release from the pituitary and has direct cardioprotective effects independent of GH secretion.
Benefits of Hexarelin: Potent GH release (strongest among GHRPs); Increased lean muscle mass and strength; Fat loss and body recomposition; Improved bone density; Enhanced collagen production; Direct cardioprotective effects; Accelerated healing
Hexarelin dosage: Cycle 8-12 weeks then take a break to avoid desensitization.
Hexarelin half-life: 30-70 minutes
Research status: Research Only
Source: PeptideWiki — https://www.peptide-wiki.net/peptides/hexarelin
Mechanism of Action
Hexarelin is a 6-amino acid synthetic peptide that binds both the GHS-R receptor and the CD36 scavenger receptor. It stimulates strong GH release from the pituitary and has direct cardioprotective effects independent of GH secretion.
Amino Acid Sequence (6 AAs)
His-D-2-MeTrp-Ala-Trp-D-Phe-Lys-NH₂
Benefits
- Potent GH release (strongest among GHRPs)
- Increased lean muscle mass and strength
- Fat loss and body recomposition
- Improved bone density
- Enhanced collagen production
- Direct cardioprotective effects
- Accelerated healing
Side Effects & Risks
- Elevated cortisol and prolactin
- Fatigue and lethargy
- Water retention
- Potential insulin resistance
- Desensitization with prolonged use
- Headaches
Where to Buy Hexarelin
1 option across 1 vendor · Sorted cheapest first · All include direct product link
From
$29.99
All links are affiliate links — PeptideWiki earns a commission at no extra cost to you. Coupon codes apply at checkout. Prices and availability may change. Always verify COA before purchasing.
Storage & Reconstitution Guide
Storage Temperature
-20°C lyophilized, 4°C reconstituted
24 months (lyophilized), 28 days (reconstituted)
Reconstitution Solvent
Bacteriostatic water (BAC water)
Swirl gently — do not shake or vortex
Handling Notes
Protect lyophilized peptide from moisture and light. Once reconstituted, keep refrigerated. Discard if solution becomes cloudy or discolored. Use insulin syringe for precise dosing.
Step-by-Step Reconstitution
Gather supplies
BAC water, insulin syringe, alcohol swabs, vial
Disinfect tops
Swab rubber stoppers of both vials with alcohol
Draw BAC water
Pull desired mL of BAC water into syringe
Inject slowly
Inject BAC water down the side of the peptide vial, swirl gently to dissolve
Molecular Structure
- CAS Number
- 140703-51-1
- PubChem CID
- 6918297
- Molecular Weight
- 887.04 Da
- Mol. Formula
- C47H58N12O6
- Amino Acids
- 6-AA peptide
- Wikipedia
- View article
Research Protocol
- Dose Range
- 200–300 mcg
- Frequency
- 1-3x daily subcutaneous injection
- Cycle
- 8-12 weeks
- Half-Life
- 30-70 minutes
- Routes
- subcutaneous injection
- Notes
- Cycle 8-12 weeks then take a break to avoid desensitization.
Legal & Regulatory Status
Sold for research purposes only. Not for human use. Laws vary by country.
Commonly Stacked With
View all peptide stacks →External Resources
PeptideWiki Research Team
Evidence-based research data sourced from PubMed and ClinicalTrials.gov · Last updated: February 25, 2026
Frequently Asked Questions About Hexarelin
What is Hexarelin?▾
A synthetic hexapeptide GHRP with the highest GH-releasing potency among the GHRP family. Notable for both its muscle-building effects and documented cardiovascular benefits.
What are the benefits of Hexarelin?▾
Potent GH release (strongest among GHRPs)
What are the benefits of Hexarelin?▾
Increased lean muscle mass and strength
What are the side effects of Hexarelin?▾
Elevated cortisol and prolactin
What is the recommended dosage for Hexarelin?▾
Cycle 8-12 weeks then take a break to avoid desensitization.
How long should a Hexarelin cycle last?▾
8-12 weeks
More Body Composition Peptides
View all Body Composition peptides →MK-677 (Ibutamoren)
Ibutamoren
A non-peptide, orally active growth hormone secretagogue that mimics ghrelin, significantly elevating GH and IGF-1 levels. Unique in being orally bioavailable.
CJC-1295 No DAC (Mod GRF 1-29)
Modified GRF 1-29
A synthetic 29-amino acid GHRH analog with 4 amino acid substitutions that improve stability and receptor affinity compared to Sermorelin. Unlike CJC-1295 DAC, it has no Drug Affinity Complex, giving it a short 30-minute half-life that mimics the body's natural pulsatile GHRH secretion when co-administered with a GHRP.
Follistatin-344
FST-344
A naturally occurring protein that inhibits myostatin and activin, effectively removing the biological ceiling on muscle growth.
MGF (Mechano Growth Factor)
Mechano Growth Factor
A splice variant of IGF-1 released in muscle fibers in response to mechanical damage. Activates muscle satellite cells to initiate repair and hypertrophy.