Ovagen
Also known as: Ovarian peptide bioregulator · Female gonadal bioregulator · Zhenoluten
A peptide bioregulator targeting ovarian tissue from the Khavinson series. Studied for female reproductive aging, premature ovarian insufficiency, menopause symptom management, and ovarian reserve support. Normalizes follicular cell function and ovarian hormone synthesis.
Mechanism of Action
Ovagen activates gene expression in granulosa and thecal cells that regulate folliculogenesis and estrogen/progesterone synthesis. It restores age-related decline in ovarian sensitivity to FSH and LH signaling, reduces apoptosis in follicular cells, and normalizes the pituitary-ovarian hormonal axis without being an exogenous hormone.
Benefits
- Normalizes ovarian cell function and hormone synthesis
- Non-hormonal approach to female reproductive aging
- Reduces premature ovarian insufficiency progression
- Supports ovarian reserve in perimenopausal women
- Menopause symptom research
- Normalizes FSH/LH sensitivity
- Female fertility support research
Side Effects & Risks
- Monitor FSH, LH, estradiol levels during use
- Generally well tolerated
- Injection site reactions
Where to Buy Ovagen
1 option across 1 vendor · Sorted cheapest first · All include direct product link
From
$49.99
All links are affiliate links — PeptideWiki earns a commission at no extra cost to you. Coupon codes apply at checkout. Prices and availability may change. Always verify COA before purchasing.
Storage & Reconstitution Guide
Storage Temperature
-20°C (lyophilized)
24 months (lyophilized), 28 days (reconstituted)
Reconstitution Solvent
Bacteriostatic water (BAC water)
Swirl gently — do not shake or vortex
Handling Notes
Protect lyophilized peptide from moisture and light. Once reconstituted, keep refrigerated. Discard if solution becomes cloudy or discolored. Use insulin syringe for precise dosing.
Step-by-Step Reconstitution
Gather supplies
BAC water, insulin syringe, alcohol swabs, vial
Disinfect tops
Swab rubber stoppers of both vials with alcohol
Draw BAC water
Pull desired mL of BAC water into syringe
Inject slowly
Inject BAC water down the side of the peptide vial, swirl gently to dissolve
Research Protocol
- Dose Range
- 1–2 mg
- Frequency
- Daily for 10-day courses
- Cycle
- 10-day courses, 2x per year
- Routes
- subcutaneous injection
- Notes
- Standard Khavinson protocol: 1-2mg/day for 10 days, 2x per year. Monitor estradiol, FSH, LH. Often combined with Epithalon for comprehensive female anti-aging.
Legal & Regulatory Status
Sold for research purposes only. Not for human use. Laws vary by country.
Commonly Stacked With
View all peptide stacks →External Resources
Chemical Properties
- Mol. Weight
- ~480 Da
More in Sexual Health
Testes peptide bioregulator
A tetrapeptide (Lys-Glu-Asp-Glu estimated) testes-targeting bioregulator from the Khavinson series. Normalizes Leydig cell function, testosterone synthesis, and testicular morphology. Used in male reproductive aging, hypogonadism research, and testosterone support protocols.
Human Menopausal Gonadotropin
A urinary-derived combination of LH and FSH used clinically for fertility treatment and in TRT protocols for testicular stimulation and spermatogenesis support.
Bremelanotide
An FDA-approved melanocortin agonist for hypoactive sexual desire disorder (HSDD) in premenopausal women. Acts centrally via the CNS to increase sexual desire and arousal in both men and women.
Trans-clomiphene
The active trans-isomer of clomiphene citrate that acts as a selective estrogen receptor modulator (SERM). Blocks pituitary estrogen receptors to increase LH/FSH production and downstream testosterone synthesis. Studied for male hypogonadism as an alternative to TRT that preserves fertility and natural testosterone production.