Ovagen
Also known as: Ovarian peptide bioregulator · Female gonadal bioregulator · Zhenoluten
A peptide bioregulator targeting ovarian tissue from the Khavinson series. Studied for female reproductive aging, premature ovarian insufficiency, menopause symptom management, and ovarian reserve support. Normalizes follicular cell function and ovarian hormone synthesis.
What is Ovagen? A peptide bioregulator targeting ovarian tissue from the Khavinson series. Studied for female reproductive aging, premature ovarian insufficiency, menopause symptom management, and ovarian reserve support. Normalizes follicular cell function and ovarian hormone synthesis.
How does Ovagen work? Ovagen activates gene expression in granulosa and thecal cells that regulate folliculogenesis and estrogen/progesterone synthesis. It restores age-related decline in ovarian sensitivity to FSH and LH signaling, reduces apoptosis in follicular cells, and normalizes the pituitary-ovarian hormonal axis without being an exogenous hormone.
Benefits of Ovagen: Normalizes ovarian cell function and hormone synthesis; Non-hormonal approach to female reproductive aging; Reduces premature ovarian insufficiency progression; Supports ovarian reserve in perimenopausal women; Menopause symptom research; Normalizes FSH/LH sensitivity; Female fertility support research
Ovagen dosage: Standard Khavinson protocol: 1-2mg/day for 10 days, 2x per year. Monitor estradiol, FSH, LH. Often combined with Epithalon for comprehensive female anti-aging.
Research status: Research Only
Source: PeptideWiki — https://www.peptide-wiki.net/peptides/ovagen
Mechanism of Action
Ovagen activates gene expression in granulosa and thecal cells that regulate folliculogenesis and estrogen/progesterone synthesis. It restores age-related decline in ovarian sensitivity to FSH and LH signaling, reduces apoptosis in follicular cells, and normalizes the pituitary-ovarian hormonal axis without being an exogenous hormone.
Benefits
- Normalizes ovarian cell function and hormone synthesis
- Non-hormonal approach to female reproductive aging
- Reduces premature ovarian insufficiency progression
- Supports ovarian reserve in perimenopausal women
- Menopause symptom research
- Normalizes FSH/LH sensitivity
- Female fertility support research
Side Effects & Risks
- Monitor FSH, LH, estradiol levels during use
- Generally well tolerated
- Injection site reactions
Where to Buy Ovagen
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$49.99
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Storage & Reconstitution Guide
Storage Temperature
-20°C (lyophilized)
24 months (lyophilized), 28 days (reconstituted)
Reconstitution Solvent
Bacteriostatic water (BAC water)
Swirl gently — do not shake or vortex
Handling Notes
Protect lyophilized peptide from moisture and light. Once reconstituted, keep refrigerated. Discard if solution becomes cloudy or discolored. Use insulin syringe for precise dosing.
Step-by-Step Reconstitution
Gather supplies
BAC water, insulin syringe, alcohol swabs, vial
Disinfect tops
Swab rubber stoppers of both vials with alcohol
Draw BAC water
Pull desired mL of BAC water into syringe
Inject slowly
Inject BAC water down the side of the peptide vial, swirl gently to dissolve
Research Protocol
- Dose Range
- 1–2 mg
- Frequency
- Daily for 10-day courses
- Cycle
- 10-day courses, 2x per year
- Routes
- subcutaneous injection
- Notes
- Standard Khavinson protocol: 1-2mg/day for 10 days, 2x per year. Monitor estradiol, FSH, LH. Often combined with Epithalon for comprehensive female anti-aging.
Legal & Regulatory Status
Sold for research purposes only. Not for human use. Laws vary by country.
Commonly Stacked With
View all peptide stacks →External Resources
Chemical Properties
- Mol. Weight
- ~480 Da
PeptideWiki Research Team
Evidence-based research data sourced from PubMed and ClinicalTrials.gov · Last updated: February 25, 2026
Frequently Asked Questions About Ovagen
What is Ovagen?▾
A peptide bioregulator targeting ovarian tissue from the Khavinson series. Studied for female reproductive aging, premature ovarian insufficiency, menopause symptom management, and ovarian reserve support. Normalizes follicular cell function and ovarian hormone synthesis.
What are the benefits of Ovagen?▾
Normalizes ovarian cell function and hormone synthesis
What are the benefits of Ovagen?▾
Non-hormonal approach to female reproductive aging
What are the side effects of Ovagen?▾
Monitor FSH, LH, estradiol levels during use
What is the recommended dosage for Ovagen?▾
Standard Khavinson protocol: 1-2mg/day for 10 days, 2x per year. Monitor estradiol, FSH, LH. Often combined with Epithalon for comprehensive female anti-aging.
How long should a Ovagen cycle last?▾
10-day courses, 2x per year
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